Impacts of nutritive and bioactive compounds on cancer development and therapy

Sultana, Sabira; Bouyahya, Abdelhakim; Rebezov, Мaksim; Shariati, Mohammad Ali; Balahbib, Abdelaali; Khouchlaa, Aya; Yaagoubi, Ouadie Mohamed El; Khaliq, Adnan; Omari, Nasreddine El; Bakrim, Saad; Zengin, Gökhan; Akram, Muhammad; Khayrullin, Mars; Bogonosova, I. A.; Mahmud, Shafi; Simal-Gándara, Jesús

doi:10.1080/10408398.2022.2062699

Cited by 5 publications

(3 citation statements)

References 281 publications

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“…Органолептические характеристики полученных образцов оценивались согласно методике ГОСТ 5667 8 . Влажность образцов определяли по методике ГОСТ 21094 9 , кислотность -по ГОСТ 5670 10 , пористость -по ГОСТ 5669 11 , формоустойчивостьпо ГОСТ 27669 12 , массовую долю белка -согласно методике ГОСТ 10846 13 , массовую долю жиров -согласно методике ГОСТ 29033 14 , массовую долю углеводов -перманганатометрическим методом согласно ГОСТ 13496.4 15 , содержание клетчатки -методом Венде по ГОСТ 31675 16 , содержание кальция, железа, магния и цинка -методом атомно-абсорбционной AGROENGINEERING AND FOOD TECHNOLOGIES АГРОИНЖЕНЕРИЯ И ПИЩЕВЫЕ ТЕХНОЛОГИИ спектрометрии по методике ГОСТ 22001 17 , содержание кремния -по методике ГОСТ 13230.1 18 , витаминный состав -методом жидкостной хроматоографии [12] согласно ГОСТ 34151 19 , аминокислотный состав -по методу, приведенному в ГОСТ 32195 20 .…”

Section: материалы и методы исследований / Materials and Methodsunclassified

“…Другим немаловажным показателем является антиоксидантная активность, потому что она считается неотъемлемой частью здорового питания. Столь высокий интерес к антиоксидантам объясняется их способностью возможностью блокировать воздействие на организм свободных радикалов и вследствие этого предотвращать человека от стремительного развития заболеваний и старения [13]. Антиоксидантная активность (расчетный метод) в хлебе из зернобобовой смеси составила 34,39 ± 1,04 / 100 г.…”

Section: агроинженерия и пищевые технологииunclassified

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The use of leguminous mixture for bakery products

Rustemova,

Rebezov

2023

Agrarnaâ nauka

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The main criterion of the country's food security is the stable provision of the population with high-quality food products using scientific developments. For Kazakhstan and Russia, grain is the main agricultural raw material, and grain-based products are one of the main inexpensive sources of nutrients. Bread is a fundamental product in the diet of most citizens of Russia and Kazakhstan, therefore, improving its nutritional properties and creating functional products based on it is an urgent task for the food industry. The paper presents the results of a study on the development of bread products with the addition of a leguminous mixture on sourdough. The leguminous mixture consists of seven cereals and legumes: oats, corn, millet, buckwheat, soy, peas (mash), Chinese beans. Four samples of bread were made with the addition of 5%, 7%, 10%, 12% leguminous mixture to the mass of wheat flour on sourdough and control samples. It has been established that the use of bread with the addition of a 10% leguminous mixture on sourdough contributes to the increase in the nutritional and biological value of products in terms of protein, carbohydrates, vitamins, dietary fiber and minerals, which allows more efficient use of raw plant resources of the Republic of Kazakhstan and the Russia.

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Section: материалы и методы исследований / Materials and Methodsunclassified

Section: агроинженерия и пищевые технологииunclassified

The use of leguminous mixture for bakery products

Rustemova,

Rebezov

2023

Agrarnaâ nauka

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“…The proteasome is localized in the nucleus and cytoplasm of eukaryotic cells, although its subcellular distribution varies from one organ to another [ 7 ]. Because the ubiquitin–proteasome system interferes with various cellular metabolic processes, deregulation of these components can cause many diseases, including neurodegenerative diseases, certain cancers, and autoimmune diseases [ 8 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

Functional and quantitative evaluation of the 20S proteasome in serum and intracellular in145 moroccan patients with hematologic malignancies

et al. 2022

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Background Regulatory degradation of intracellular proteins plays an essential role in most biological processes, particularly in the control of cell proliferation and differentiation. In eukaryotes, intracellular proteolysis is largely provided by the Ubiquitin / Proteasome system. Alterations and dysfunction of protein degradation by the Ubiquitin / Proteasome system, such as transcription factors, cell cycle regulators or tumor suppressor proteins, have been linked to human. Pathologies, including blood cancers. Mainly localized in the nucleus and cytoplasm of cells, the proteasome can be detected in the cell culture supernatant or in the peripheral blood of patients. This study deals with the problems of the search for serum markers specific to certain pathologies and which would be useful in the prevention, diagnosis and monitoring of cancers and which could be used as a therapeutic tool. Methods The functional and quantitative analysis of the proteasome is carried out at the serum and subcellular level during a pathological phenomenon in a population of 145 Moroccan patients (sex ratio: 1.10 / average age: 47.9 ± 15, 3 years) using an indirect ELISA test and a follow-up of the fluorescence emitted after enzymatic digestion of specific peptides by proteolytic activity (chymotrypsin-like). Results The evolutionary trend proteasome subcellular is significantly linked to the rate of chymotrypsin-like activity. The entire population of 60 patients called back for a second blood test. After three months of treatment reported a significant drop in the rate and the activity of the proteasome in serum and intracellular level. Conclusions Although the serum proteasome level is a potential new tool for the monitoring of. Patientswithliquid cancer. Trial registration: retrospectively registered.

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Evaluation of the antioxidant and antimicrobial activity of plant bioactive compounds as natural preservatives

Orlova,

El-Sohaimy,

Rebezov

2023

Agrarnaâ nauka

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Relevance. Natural preservatives such as salt or sugar can be harmful to human health if consumed in excess. Artificial preservatives often use synthetic chemicals that are considered safe by the FDA. A more serious health problem associated with artificial preservatives is that they are often found in unhealthy, processed foods.Methods. The monographic method was used in the work, as well as methods of analysis, systematization, comparison, generalization. The search for data sources was carried out in scientific electronic libraries and search engines eLIBRARY.ru, Science Direct, Scopus, ResearchGate and Cyberleninka portals.Results. Apple peel extract showed high antioxidant activity and effectively slowed down lipid oxidation. At a concentration of 50 micrograms/ml, the OH removal activity was 57%. The antibacterial activity of sea buckthorn seeds is 200–350 mcg/ml, expressed in a minimum inhibitory concentration against various grampositive and gram-negative bacteria, the antioxidant activity is 40,379–93,473, expressed as a percentage.Antioxidant phenolic compounds present in the seeds and skins (meal) of grapes account for 60–70% of the total polyphenols in grapes.Total antioxidant activity for black currant leaves. was 44.51 ± 1.72%.Summing up the comparison of the antioxidant activity of the selected sources, we can conclude that the source that showed the highest antioxidant activity is grape cake. However, if we pay attention to the climatic factor, in the conditions of the Russian Federation it is most expedient to use the peel of apples with an antioxidant activity of 57%, in view of the abundance of this product and the ease of its cultivation

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Impacts of nutritive and bioactive compounds on cancer development and therapy

Cited by 5 publications

References 281 publications

The use of leguminous mixture for bakery products

The use of leguminous mixture for bakery products

Functional and quantitative evaluation of the 20S proteasome in serum and intracellular in145 moroccan patients with hematologic malignancies

Evaluation of the antioxidant and antimicrobial activity of plant bioactive compounds as natural preservatives

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