This study attempts to test the effect of trade openness, exchange rate and oil price on the exports in Syria over the period . The cointegration test indicates that exports are positively related to trade openness and oil price, but negatively related to exchange rate. Exchange rate has the biggest effect on the exports. The Granger causality test indicates bidirectional causality relationships between trade openness, exchange rate, oil price and exports in the short and long run. The study result indicates that, in order to boost the Syrian exports, it is vital for the Syrian government to open up the Syrian economy to foreign trade, decline the Syrian pound exchange rate, improve the quality of the Syrian exports, and decline the crude oil exports.