Impaired fasting glucose in breast cancer survivors of a general hospital at Mexico City: A case series study

Ortiz-Mendoza, Carlos Manuel

doi:10.4103/jrms.jrms_353_18

Cited by 4 publications

(2 citation statements)

References 13 publications

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“…[62] Obesity is considered as one of the predisposing factors for cancer even in nondiabetic individuals with impaired fasting glucose levels. [63] Other sex-related cancers such as endometrial and prostate cancer are also studied, yet the results of most of the studies are inconclusive. A strong positive association of diabetes with increased risk of endometrial cancer has been reported in females in meta-analysis of 13 case–control and 3 cohort studies.…”

Section: Introductionmentioning

confidence: 99%

Diabetes and cancer: A comprehensive review

Abudawood

2019

J Res Med Sci

113

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Diabetes mellitus (DM) is a common worldwide endocrine disorder characterized by hyperglycemia resulting from defects in insulin secretion and insulin action or both. A number of clinical studies have investigated diabetes and its causal relation with neoplasm. Several epidemiological studies have found that diabetic patients have an increased risk of different types of cancers, for example liver, pancreas, gastric (stomach), colorectum, kidney, and breast, and it is predicted that hyperglycemic state observed in diabetic milieu enhances the cancer risk in prediabetic and diabetic individuals. To explore the strength of evidence and biases in the claimed associations between type 2 DM (T2DM) and risk of developing cancer, an umbrella review of the evidence across published meta-analyses or systematic reviews is performed. The concurrence of T2DM with the growing burden of cancer globally has generated interest in defining the epidemiological and biological relationships between these medical conditions. Through this review, it was found that diabetes could be related to cancer. Yet, the results from most of the studies are obscure and conflicting and need a robust research so that the link between diabetes and cancer could be firmly and impeccably documented.

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Section: Introductionmentioning

confidence: 99%

Diabetes and cancer: A comprehensive review

Abudawood

2019

J Res Med Sci

113

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“…Breast cancer is one of the most common malignancies in women worldwide. [ 1 2 3 4 ] Although the reported incidence of this cancer is higher in developed countries, its mortality rate is higher in less developed countries. [ 5 6 7 8 9 ] This cancer is one of the important causes of death in women.…”

Section: Introductionmentioning

confidence: 99%

Association between serum Vitamin D levels and prognostic factors in nonmetastatic breast cancer patients

Mirzaei

Shahrzad

Gharehgozlou

et al. 2022

Journal of Research in Medical Sciences

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Background: Breast cancer is among the most common malignancies in women around the world. There is evidence of high prevalence of serum/blood Vitamin D deficiency in Iranian women. Considering the multitude of factors that may be involved in the prognosis and lifespan of breast cancer patients, this study investigated the level of Vitamin D in Iranian patients with nonmetastatic breast cancer. Materials and Methods: This cross-sectional study was carried out on 214 women diagnosed with breast cancer, who were referred to the radio-oncology department. Serum Vitamin D level of the patients was measured. Prognostic factors were determined based on demographic and pathological characteristics. The results were analyzed using descriptive statistics tests, Chi-square, one-way analysis of variance, Kaplan–Meier, and Cox regression model in SPSS v22. For all cases, the significance level was considered to be P < 0.05. Results: The total mean of 25-hydroxyvitamin D serum level was 25.15 ± 17.68 ng/ml. There was no significant relationship between levels of Vitamin D with disease stage, tumor size, tumor grade, estrogen receptor, progesterone receptor, and Human epidermal growth factor receptor 2 ( P > 0.05). The mean survival time was 5 years and 45 days. Conclusion: No relationship was found between serum Vitamin D levels and the factors affecting the prognosis of nonmetastatic breast cancer. The Cox analysis showed that the survival time was not influenced by Vitamin D as a prognosis factor.

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The diabetes mellitus and oncopathоlogy

Zhuravlyova¹,

Сокольнікова²

2021

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The number of newly diagnosed cases of diabetes mellitus (DM) and various cancers is growing every year. Obviously, the presence of one disease significantly complicates the course of another. But it is still unclear whether diabetes potentiates the development of cancer or oncopathology will be the cause of carbohydrate metabolism disorders, and what effect the use of antidiabetic drugs has on the course of cancer.The purpose of this review was to establish a causal relationship between diabetes, hypoglycemic therapy and the development of oncopathology.Results. The hyperinsulinemia and hyperglycemia consistently increase the likelihood of tumor development not only in patients with diabetes but also in patients with prediabetes, and lead to some cancers, such as pancreatic, liver, stomach, colon, breast, kidney, lungs, etc. In addition, increasing or decreasing the risk of cancer may be a side effect of some antidiabetic drugs.Conclusions. Diabetes is a risk factor for cancer, especially hepatocellular, hepatobiliary, pancreatic, breast, ovarian, endometrial and gastrointestinal cancers. In general, treatment with sulfonylureas can increas the risk of cancer, while treatment associated with improved insulin resistance, such as metformin, may reduce this risk.It is obvious that many existing studies have ambiguous results and require correction due to organizational errors, ie it is necessary to conduct additional carefully planned and properly organized studies. In addition, given the importance of both diseases, we believe that diabetic patients need routine screening and orientation of medical personnel for early detection of oncopathology.

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Impaired fasting glucose in breast cancer survivors of a general hospital at Mexico City: A case series study

Cited by 4 publications

References 13 publications

Diabetes and cancer: A comprehensive review

Diabetes and cancer: A comprehensive review

Association between serum Vitamin D levels and prognostic factors in nonmetastatic breast cancer patients

The diabetes mellitus and oncopathоlogy

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