Impaired Lipid Metabolism in Metabolic Disorders

Haider, Kamran; Rehman, Kanwal; Akash, Muhammad Sajid Hamid

doi:10.1007/978-3-030-45923-9_5

Cited by 3 publications

(2 citation statements)

References 55 publications

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“…There is an enormous amount of premise on association between obesity and abnormalities in lipid metabolism mainly among women. [41][42][43][44] The data revealed, as predicted, that both systolic and diastolic blood pressure were statistically but clinically negligible higher among males compared to females, showing that no significant difference between males and females was observed. Larger populationbased research and meta-analysis indicate that across middle age, males typically have a higher blood pressure than females.…”

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confidence: 56%

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Utilizing diabetes registry for exploring sociodemographic and clinical characteristics of type II diabetic patients in Saudi Arabia

Tourkmani

Alharbi

Rsheed

et al. 2021

SMJ

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Objectives: To explore the sociodemographic and clinical characteristics as the process and outcomes of diabetic individuals. Methods: Hospital Saudi registry at Prince Sultan Military Medical city, Chronic Illness Clinics (Family and Community Medicine), Riyadh, Saudi Arabia database was started in February 2019 and data were collected until February 2020. The data were collected by trained diabetes nurse specialists. The registry includes all patients with type II diabetes mellitus (DM) and excluded patients with type I DM. Results: A total of 8,209 patients were enrolled in the registry with a higher proportion of females than males. The mean age was 59.3 years, BMI 32.5kg/m 2 , and HBA1c levels was 8.2%. Significant gender differences for BMI, duration of diabetes, blood pressure, LDL, smoking status, and medication intake. From the first to the third visit, BMI was raised; however, LDL, diastolic blood pressure, and albumin creatinine ratio were reduced. The mean HBA1c values plummeted for all patients and 33% of the patients had a reduction in the HbA1c levels. However, HbA1c levels increased for 24.7% of the patients’ from baseline to the last visit. Conclusion: This registry provides great insights into the sociodemographic and clinical characteristics of diabetic patients in Saudi Arabia. This registry data can be used to investigate the associations between sociodemographic or clinical characteristics and glycemic control among T2DM patients in Saudi Arabia.

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confidence: 56%

“…There is an enormous amount of premise on association between obesity and abnormalities in lipid metabolism mainly among women. 41 - 44 …”

Section: Discussionmentioning

confidence: 99%

Utilizing diabetes registry for exploring sociodemographic and clinical characteristics of type II diabetic patients in Saudi Arabia

Tourkmani

Alharbi

Rsheed

et al. 2021

SMJ

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Adherence to Treatment and Glycemic Control in Patients with Type 2 Diabetes Mellitus: A 4-Year Follow-up PTM Bogor Cohort Study, Indonesia

Kaaffah

Soewondo

Riyadina

et al. 2021

PPA

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A Current Review on Diabetes Mellitus Induced Gut Microbiota and Histological Changes

Ragbetli,

Keskin

2023

Current Multidisciplinary Approach to Diabetes Mellitus Occurrence Mechanism

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Recent studies have highlighted the intricate relationship between diabetes mellitus (DM) and alterations in gut microbiota composition, as well as associated histological changes. Dysbiosis, characterized by an imbalance in microbial communities, has been observed in diabetic individuals, with decreased microbial diversity and altered abundance of specific taxa such as Firmicutes and Bacteroidetes. These changes are implicated in promoting systemic inflammation, insulin resistance, and metabolic dysfunction. Concurrently, diabetic conditions influence gut barrier integrity and mucosal immunity, leading to histological alterations such as increased intestinal permeability and inflammation. The bidirectional interactions between gut microbiota and host metabolism underscore the potential of targeting the gut microbiome as a therapeutic approach in managing DM and its complications. Further research into the mechanistic links between gut microbiota dysbiosis, histological changes, and metabolic outcomes is crucial for developing targeted interventions to improve diabetic outcomes.

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Impaired Lipid Metabolism in Metabolic Disorders

Cited by 3 publications

References 55 publications

Utilizing diabetes registry for exploring sociodemographic and clinical characteristics of type II diabetic patients in Saudi Arabia

Utilizing diabetes registry for exploring sociodemographic and clinical characteristics of type II diabetic patients in Saudi Arabia

Adherence to Treatment and Glycemic Control in Patients with Type 2 Diabetes Mellitus: A 4-Year Follow-up PTM Bogor Cohort Study, Indonesia

A Current Review on Diabetes Mellitus Induced Gut Microbiota and Histological Changes

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