Impaired recovery of cardiac output and mean arterial pressure after successful defibrillation in patients with low left ventricular ejection fraction

Skhirtladze, Keso; Mora, Bruno; Moritz, Andrea; Birkenberg, Beatrice; Ankersmit, Hendrik Jan; Dworschak, Martin

doi:10.1016/j.resuscitation.2010.06.004

Cited by 18 publications

(19 citation statements)

References 33 publications

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“…10 In the present study, LV systolic dysfunction after DFT testing was limited in patients with reduced LVEF, and this result does not contradict previous observations that cardiac output was deteriorated only in patients with low LVEF after inductions of ICD shock. 20,21 In contrast to the effect of DFT testing on systolic function, DFT testing promoted transient diastolic dysfunction in all patients, irrespective of preoperative LVEF in the present study. Experimental studies revealed that the time constant of LV relaxation was prolonged, and LV end-diastolic pressure was increased after direct current shock even in normal hearts.…”

Section: Effect Of Icd Shock On Cardiac Functioncontrasting

confidence: 83%

Cardiac Dysfunction and Prolonged Hemodynamic Deterioration After Implantable Cardioverter-Defibrillator Shock in Patients With Systolic Heart Failure

Toh

Nishii

Nakamura

et al. 2012

Circ: Arrhythmia and Electrophysiology

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Background-We investigated the acute effects of implantable cardioverter-defibrillator shock on myocardium, cardiac function, and hemodynamics in relation to left ventricular systolic function. Methods and Results-We studied 50 patients who underwent implantable cardioverter-defibrillator implantation and defibrillation threshold (DFT) testing: 25 patients with left ventricular ejection fraction (LVEF) ≥45% and 25 patients with LVEF <45%. We measured cardiac biomarkers (creatine kinase, creatine kinase-MB, myoglobin, cardiac troponin T and I, and N-terminal probrain natriuretic peptide). Left ventricular relaxation was assessed by global longitudinal strain rate during the isovolumetric relaxation period using speckle-tracking echocardiography. Blood sampling and echocardiography were performed before, immediately after, and 5 minutes and 4 hours after DFT testing. Mean arterial pressure was measured directly during DFT testing. Cardiac biomarkers showed no significant changes in either group. LVEF was decreased until 5 minutes after DFT testing and had recovered to the baseline at 4 hours in the group with reduced LVEF (P<0.001), whereas LVEF reduction was not observed in the group with preserved LVEF (P=0.637). Global isovolumetric relaxation period was decreased until 5 minutes after DFT testing and had recovered to the baseline at 4 hours in both groups (preserved LVEF: 0.39±0.14 versus 0.23±0.13* versus 0.23±0.13* versus 0.40±0.13 s

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Section: Effect Of Icd Shock On Cardiac Functioncontrasting

confidence: 83%

Cardiac Dysfunction and Prolonged Hemodynamic Deterioration After Implantable Cardioverter-Defibrillator Shock in Patients With Systolic Heart Failure

Toh

Nishii

Nakamura

et al. 2012

Circ: Arrhythmia and Electrophysiology

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show abstract

“…These patients may need inotropic agents or mechanical ventricular support [49][50][51]. rSO 2 can be used to monitor brain oxygenation and guide the care provider to make either pharmacological or device adjustments to optimize brain oxygenation.…”

Section: Post Restoration Of Spontaneous Circulationmentioning

confidence: 99%

Near-infrared spectroscopy during cardiopulmonary resuscitation and after restoration of spontaneous circulation

Wik

2016

Current Opinion in Critical Care

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“…There might, however, be some selection bias involved as ECPR was predominantly deployed a) during daytime, b) in nonelderly male adults, who had c) witnessed arrest with d) brief CPR and e) an initially shockable rhythm. Nevertheless, ECPR does allow extension of CPR duration (5) and stabilization of hemodynamics when cardiac pump function is likely critically impaired (6). Further potentially life-saving interventions such as intra-arrest percutaneous coronary intervention (7), moderate hypothermia, heart transplantation, implantation of left ventricular assist devices, etc., have consequently been carried out in ECPR patients more often (4).…”

Section: Is Extracorporeal Cardiopulmonary Resuscitation For Out-of-hmentioning

confidence: 99%

Impaired recovery of cardiac output and mean arterial pressure after successful defibrillation in patients with low left ventricular ejection fraction

Cited by 18 publications

References 33 publications

Cardiac Dysfunction and Prolonged Hemodynamic Deterioration After Implantable Cardioverter-Defibrillator Shock in Patients With Systolic Heart Failure

Cardiac Dysfunction and Prolonged Hemodynamic Deterioration After Implantable Cardioverter-Defibrillator Shock in Patients With Systolic Heart Failure

Near-infrared spectroscopy during cardiopulmonary resuscitation and after restoration of spontaneous circulation

Is Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest Superior Compared With Conventional Resuscitation?*

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