Impaired regional diastolic distensibility in coronary artery disease: Relations with dynamic left ventricular compliance

Pouleur, H.; Rousseau, Michel F.; Eyll, Christian van; Gurne, Olivier; Hanet, Claude; Charlier, Aa.

doi:10.1016/0002-8703(86)90466-7

Cited by 10 publications

(1 citation statement)

References 28 publications

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“…A second limitation of the study is the absence of coronary arteriographic data. Diastolic filling variables can be adversely affected by ischemic heart disease 36–38 . We cannot exclude the possibility that some of our elderly subjects had clinically occult coronary artery disease.…”

Section: Discussionmentioning

confidence: 96%

Left Ventricular Diastolic Filling in Elderly Hypertensive Patients

Nicolino

Ferrara²,

Longobardi

et al. 1993

J American Geriatrics Society

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Objective: To evaluate the effects of mild to moderate hypertension and of LVH on diastolic filling and other Doppler indices in the elderly. Design: Survey with a control group. Subjects: Seventy‐one hypertensives (34 men, 37 women) referred for echocardiograms and 32 age‐ and sex‐matched normotensive volunteers. Thirty‐six of the hypertensives had LVH; 34 did not. Setting: Echocardiography laboratory. Measurements: M‐mode, two‐dimensional, and pulsed Doppler echocardiograms. A wide variety of Doppler‐derived indices of diastolic function were assessed. Results: All Doppler derived indices of left ventricular diastolic filling (peak E, peak A, their ratio, EF slope, time‐velocity integrals, atrial filling fraction, and isovolumic relaxation time) were similar among the three groups. Conclusion: Elderly mild to moderate hypertensives with or without LVH have LV diastolic filling that is normal for age. The identification of pathological diastolic dysfunction requires comparison to age‐matched controls, since aging, a major factor influencing diastolic filling, can mask the effect of hypertension.

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Section: Discussionmentioning

confidence: 96%