The form and size of the female gluteal region have always symbolized beauty and sexuality. There is a remarkable increase in the number of patients seeking gluteoplasty worldwide. Gluteoplasty may be achieved by silicone implant insertion or autologous fat transfer, in addition to other ancillary procedures including liposuction. Careful patient selection and evaluation are needed to assure good results. The aim of the study was to evaluate the use of silicone implants, autologous fat transfer, and liposuction in gluteoplasty. A total of 22 patients underwent gluteoplasty. Intramuscular gluteal implant insertion was employed in 8 patients, whereas autologous fat transfer was employed in 14 patients. The average patient satisfaction (on a scale from 1 to 5) following implant gluteoplasty was 4.25 for the overall aesthetic outcome, whereas the average patient satisfaction following autologous fat transfer gluteoplasty was 4.79 for the overall aesthetic outcome. Both gluteoplasties with silicone implants or fat transfer achieved favorable results, with very good to excellent patients' satisfaction after both procedures, with slightly better satisfaction following autologous fat transfer. Our results are comparable with before published results, with favorable outcomes regarding complications. Liposuction is an important addition that positively affects the aesthetic result. Gluteoplasty using silicone implants or fat transfer, in addition to ancillary liposuction, achieved favorable results, with very good to excellent patients' satisfaction. However, a larger scale study is needed to statistically approve or disapprove to this trend.