Impairment of quality of life in patients with antiphospholipid syndrome

Abstract

Compared to the general population, APS patients experienced a lower HRQoL. In these patients, a history of arterial thrombosis significantly impaired HRQoL. Therefore, measurements of HRQoL should be included in APS patient management to assess the burden of the disease from a patient's perspective and to provide patients with the support they need.

Quality of life in patients with antiphospholipid syndrome is related to disease burden and anticoagulant therapy

“…HRQoL is an important outcome in rheumatic diseases. Herein we confirm that HRQoL is impaired in PAPS patients when compared with healthy subjects as reported in Caucasian populations . Furthermore, we found that the deterioration in HRQoL was associated with the use of anticoagulants and accrual damage in the vascular domain.…”

“…Health‐related quality of life (HRQoL) is therefore an important outcome in these patients. In this regard, three recent studies reported impaired HRQoL in PAPS patients when compared with age‐matched healthy Caucasian populations . Zuily et al .…”

“…Zuily et al . reported that a history of arterial thrombosis was the major factor affecting HRQoL . Other authors found that PAPS patients have significantly worse HRQoL scores in mental domains, but better than systemic lupus erythematosus (SLE) patients in physical domains .…”

Influence of Secondary Antiphospholipid Syndrome and Secondary Sjögren’s Syndrome on Patient’s Quality of Life with Systemie Lupus Erythematosus

“…The study involved 163 women with SLE, the control group consisted of 1,045 people. Similarly Zuily et al [60] found that in the general population, patients with SLE have a lower QOL. In these patients, congested blood was a common finding,, which compromise their QOL.…”

“…Zuily et al [60] evaluated the QOL in patients with APS. Researchers have shown that the QOL of patients with APS is lower than in healthy volunteers.…”