Impedance Spectroscopy-Based Detection of Viral RNA From Clinical Samples

Saha, Ranamay; Singh, Santokh; Samal, Jasmine; Gupta, Ekta; Bhattacharya, Shantanu

doi:10.1109/lsens.2023.3297368

Cited by 2 publications

(1 citation statement)

References 18 publications

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“…3 Gradually, the integration of microfluidics and microelectronics led to the development of the term, 'lab on a chip'. 4 Microfluidic devices since then have found specific applications in multiple domains such as cellular analysis, biosensing, 5,6 environmental monitoring, 7 medicine, gas sensing and POC diagnostics [8][9][10] with beneficial aspects such as portability, lesser sample consumption and processing of multiple analytes simultaneously. 11 Microfluidic devices with complex systems assembled into simple, miniaturised, cost-effective POC diagnostic platforms in an integrated manner hold great potential for next-generation personalised healthcare system.…”

Section: Introductionmentioning

confidence: 99%

Evolution of 3d printing technology in fabrication of microfluidic devices and biological applications: a comprehensive review

Saha,

Sarkar,

Choudhury

et al. 2024

Journal of Micromanufacturing

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Lab-on-a-chip or LOC is a term that is used to describe microfluidic devices that integrate multiple analyte detection, which are normally carried out in a laboratory, into one micro-chip unit and may have applications in diverse fields such as electronics, medicine and biomedical domains. Even though microfluidics has advanced greatly during the past decade due to increased needs for portability, reduced sample requirement and multiple analyte detection capabilities biological research has not adopted the technology at the required pace. This may be owing to the time-consuming and expensive process involved in the microfabrication of biochips, the requirement of specialised setup facilities and the extremely high cost associated with microfluidics as compared to conventional technologies. In recent years, three-dimensional (3D) printing has piqued curiosity in the scientific community. It has the potential to create complex, high-resolution structures and that too in a short timeframe depending upon device complexity. This could inspire progressive research in microfluidics, particularly finding applications in biomedical engineering and point-of-care diagnostics. This article gives an overview of how 3D printing aids in the manufacture of microfluidic devices for biological applications, as well as the existing 3D printing methods which are utilised for fabrication and the future perspective in the development of microfluidic devices.

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Section: Introductionmentioning

confidence: 99%

Evolution of 3d printing technology in fabrication of microfluidic devices and biological applications: a comprehensive review

Saha,

Sarkar,

Choudhury

et al. 2024

Journal of Micromanufacturing

Self Cite

View full text Add to dashboard Cite

show abstract

Review of electrokinetic flows and their applications in BioMEMS sensors

Bhatt,

Bhattacharya,

Vashist

2024

Journal of Micromanufacturing

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BioMEMS integrates various interdisciplinary research domains to facilitate biological detection of analytes on electromechanically integrated microchips. It inherently utilizes electrical supplies to the system to serve the detection in many ways except colorimetric detection. In the context of microchip-based devices, the electric pulses generally serve one of the two primary purposes, either as low-level excitation signal or as a source of analyte manipulation in some manner. Among these effects, the study of the effect of electric pulses on the solution flow causing analyte manipulation is termed as electrokinetics. Depending on the kind of applied signal, there can be alternating current (AC) or direct current (DC) electrokinetics. These effects can be integrated into the detection system through various means. In this context, this review article discusses in detail the utility of integrating electrokinetics in detection, the associated parameters, the various electrokinetics effects, and their applications in biological detection. Some important applications chosen for discussion are particle pre-concentration, particle separation, particle rotation, and gene transformation.

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Impedance Spectroscopy-Based Detection of Viral RNA From Clinical Samples

Cited by 2 publications

References 18 publications

Evolution of 3d printing technology in fabrication of microfluidic devices and biological applications: a comprehensive review

Evolution of 3d printing technology in fabrication of microfluidic devices and biological applications: a comprehensive review

Review of electrokinetic flows and their applications in BioMEMS sensors

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