Impedimetric aptasensor based on zirconium–cobalt metal–organic framework for detection of carcinoembryonic antigen

Room Temperature Hydroxyl Group‐Assisted Preparation of Hydrophobicity‐Adjustable Metal‐Organic Framework UiO‐66 Composites: Towards Continuous Oil Collection and Emulsion Separation

“…Both UiO‐66(200) and P‐UiO‐66(200) exhibit distinct peaks related to zirconium (Zr 3d), oxygen (O 1s), and carbon (C 1s) in their XPS survey spectra (Figure 2b). A new peak at around 133.3 eV corresponds to the phosphorus signal (P 2p), [24] as seen in Figure 2b and Figure S3. This result provides evidence that TDPA molecules are present on the surface of P‐UiO‐66(200).…”

Electrochemical Detection of Flutamide by the Composite of Complex Based on Thiacalix[4]arene Derivatives and Reduced Graphene Oxide

“…Metal–organic frameworks (MOFs) are widely used in electrochemical sensing due to their diverse structures. − The metal ions in most MOFs have electrochemical activity, and the organic ligands have abundant active sites, which makes them have strong adsorption capacity. Dispersing carbon materials on the surface of MOFs can make the materials have a larger specific surface area and a higher conductivity, which is conducive to the enhancement of electrocatalytic signals. − The MOFs constructed by thiacalix[4]arene derivatives have attracted much attention due to their abundant active sites and large cavity structure. − However, it also has its shortcomings, such as poor electrical conductivity and low performance in the electrochemical detection of drugs. To improve electrical conductivity, carbon-based materials with good conductivity, high porosity, and large specific surface area are introduced into MOFs to form composite materials, which can effectively solve this problem. − The structure of reduced graphene oxide (RGO) is relatively stable, and it has a large specific surface area, good electrical conductivity, and some residual carboxyl, hydroxyl, and epoxy groups on the surface. , Mesoporous carbon (MC) has a large surface area, good conductivity, and high porosity so it has good adsorption capacity .…”

Aptasensors with palladium nanoparticle-modified hemin-containing metal–organic frameworks as the signal marker for detection of exosomes

“…In fact, such a sandwich structure sensing design is very popular not only for the use of peptides as capture probes, but also for the aptamers that are extolled as artificial antibodies and have a very bright prospect in biosensing applications, including sensing of exosomes. 8,9 Aptamer-based sensors, also called aptasensors, however, when using Zr-MOF-based signal markers for detecting exosomes, because the binding of the Zr 4+ to the phosphate head of the phospholipid bilayers of the exosomes could also occur to the phosphate groups of aptamers, 19–21 might often have some troublesome problems, such as false positives, or overhigh background responses, greatly limiting their applications.…”