2022
DOI: 10.22159/ijap.2022v14i2.43941
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Impending Contraceptives That Might Be a Positive Methodology Towards the Male Contraception

Abstract: The total population has been developing dramatically; be that as it may, right now, the decisions for male contraception are restricted. This study investigates continuous explores of male contraceptives. This study article is primarily based on the thought of contraception that must be needed toward the increasing population and giving the ideal strategy to control the fertility of humans and animals. This review featured the recent oral male contraceptives that may be revolutionary products in our world as … Show more

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Cited by 2 publications
(2 citation statements)
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References 76 publications
(88 reference statements)
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“…4, the values of antitumor activity are as close as possible to "1" (Pa from 0.8 to 0.9), which may indicate a high probability of a positive effect when using GAA derivatives as part of antitumor agents [27]. A review of scientific publications and the results of experiments conducted in China [28] indicate the ability of drugs containing Gossypol to suppress spermatogenesis, causing azoospermia. Our QSAR study confirmed the literature data: the probability to be active (Pa) for the majority (the exception are VMS 2 and 9) of gossypol derivatives was in the range from 0.6 to 0.8 (blue circles in see fig.…”
Section: In Silico Researchmentioning
confidence: 83%
“…4, the values of antitumor activity are as close as possible to "1" (Pa from 0.8 to 0.9), which may indicate a high probability of a positive effect when using GAA derivatives as part of antitumor agents [27]. A review of scientific publications and the results of experiments conducted in China [28] indicate the ability of drugs containing Gossypol to suppress spermatogenesis, causing azoospermia. Our QSAR study confirmed the literature data: the probability to be active (Pa) for the majority (the exception are VMS 2 and 9) of gossypol derivatives was in the range from 0.6 to 0.8 (blue circles in see fig.…”
Section: In Silico Researchmentioning
confidence: 83%
“…The ratio of male-to-female usage of contraceptives is skewed with females being extreme users of contraceptives [3].…”
Section: Introductionmentioning
confidence: 99%