2020
DOI: 10.37358/rc.20.1.7828
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Implant Associated Local Recurrence in Primary Bone Sarcoma

Abstract: Hydroxyapatite (HA) covered implants are widely used in orthopedic reconstructive surgery. Their biological benefits were highlighted by several studies in the past decades in which the most important ones are the osteoconductive and osteoinductive capacity, which enhances osteoblast adherence, proliferation and bone extracellular matrix formation. In bone sarcomas the micro-environmental changes are crucial for tumor growth, new bone formation especially in osteoblastic osteosarcomas (OS). Nowadays limb spar… Show more

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“…Internal fracture fixation, or osteosynthesis, uses metallic implants that have to meet specific requirements for orthopedic surgical use. These requirements refer to design, size, and material properties like strength, stiffness, resistance to fatigue, biocompatibility, and corrosion resistance [20][21][22]. Last but not least, pre-operative management plays an essential role and needs to be taken into account for favorable outcomes, as Table 1 presents.…”
Section: Introductionmentioning
confidence: 99%
“…Internal fracture fixation, or osteosynthesis, uses metallic implants that have to meet specific requirements for orthopedic surgical use. These requirements refer to design, size, and material properties like strength, stiffness, resistance to fatigue, biocompatibility, and corrosion resistance [20][21][22]. Last but not least, pre-operative management plays an essential role and needs to be taken into account for favorable outcomes, as Table 1 presents.…”
Section: Introductionmentioning
confidence: 99%