Within the limits of the evaluated data it can be cautiously concluded that once immediately loaded or restored implants integrate successfully, they appear to show a soft-tissue reaction with regard to periodontal as well as morphologic aspects comparable with those of conventionally loaded implants. However, follow-up periods are generally short, number of patients and/or implants per study are few, and most studies present only limited data on peri-implant soft-tissue evaluation. More accurate long-term studies with a stronger study design (i.e., RCT) reporting more detailed on treatment and follow-up protocols are required to allow for proper comparisons and conclusions.