Implantation of left ventricular assist device in a patient with left ventricular non-compaction

Balsara, Keki R.; Bierhals, Andrew J.; Vader, Justin; Pasque, Michael K.; Itoh, Aki

doi:10.1111/jocs.13088

Cited by 6 publications

(4 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…11,15 In both of our patients, LVAD implantation was performed successfully with no modification of posthospitalization anticoagulation goals or strategies or extensive intraoperative debridement. 16 To date, no thromboembolic events have occurred in either patient, offering support for LVAD therapy for patients with LVNC with intractable heart failure when the transplant is not immediately available or is contraindicated.…”

Section: Discussionmentioning

confidence: 98%

Usefulness of a left ventricular assist device in patients with left ventricular noncompaction

Hashemi

Raza

Harmon

et al. 2018

Baylor University Medical Center Proceedings

View full text Add to dashboard Cite

Left ventricular noncompaction (LVNC) is a multifactorial structural abnormality of the myocardial wall characterized by prominent trabeculae and deep trabecular recesses. LVNC may present as a congenital or acquired defect characterized by 2 distinct tissue layers: a spongy, noncompacted inner myocardium and a thin, compacted outer myocardium. Patients with LVNC are prone to thromboembolic events, either due to deep trabeculations in the noncompacted myocardium or due to arrhythmias accompanying the defect. There are sparse data concerning treatment options for patients with LVNC who fail medical management. We present 2 such patients with LVNC who, following failed medical management, received a left ventricular assist device (LVAD): one for long-term management and one as a bridge to transplant. Both were managed successfully without thromboembolic events to date. The success of these cases suggests that LVAD placement is a viable therapy in patients with LVNC as a bridge to transplant or as long-term management.

show abstract

Section: Discussionmentioning

confidence: 98%

Usefulness of a left ventricular assist device in patients with left ventricular noncompaction

Hashemi

Raza

Harmon

et al. 2018

Baylor University Medical Center Proceedings

View full text Add to dashboard Cite

show abstract

“…However, refusing HTx to pediatric NCCM patients is not grounded based on the diagnosis alone, since graft rejection and mortality after HTx is similar in NCCM and DCM patients [70]. Experience with mechanical circulatory support in pediatric patients with NCCM is scarce and limited to single cases [81][82][83]. Though it is feasible, this therapy is reserved for only NCCM patients with single, predominantly left, ventricular failure.…”

Section: Managementmentioning

confidence: 99%

State-of-the art review: Noncompaction cardiomyopathy in pediatric patients

et al. 2021

View full text Add to dashboard Cite

Noncompaction cardiomyopathy (NCCM) is a disease characterized by hypertrabeculation, commonly hypothesized due to an arrest in compaction during fetal development. In 2006, NCCM was classified as a distinct form of cardiomyopathy (CMP) by the American Heart Association. NCCM in childhood is more frequently familial than when diagnosed in adulthood and is associated with other congenital heart diseases (CHDs), other genetic CMPs, and neuromuscular diseases (NMDs). It is yet a rare cardiac diseased with an estimated incidence of 0.12 per 100.000 in children up to 10 years of age. Diagnosing NCCM can be challenging due to non-uniform diagnostic criteria, unawareness, presumed other CMPs, and presence of CHD. Therefore, the incidence of NCCM in children might be an underestimation. Nonetheless, NCCM is the third most common cardiomyopathy in childhood and is associated with heart failure, arrhythmias, and/or thromboembolic events. This state-of-the-art review provides an overview on pediatric NCCM. In addition, we discuss the natural history, epidemiology, genetics, clinical presentation, outcome, and therapeutic options of NCCM in pediatric patients, including fetuses, neonates, infants, and children. Furthermore, we provide a simple classification of different forms of the disease. Finally, the differences between the pediatric population and the adult population are described.

show abstract

“…The standard approach for left ventricular assist device (LVAD) implantation is full sternotomy; it is done as the "first choice" in many centers around the world based on the long-term experience. The advantages of this approach are various: certainly full sternotomy provides the best anatomical overview of the heart and the major vessel and structures; moreover full sternotomy allows to approach different procedures that can be correlated and necessary to the LVAD implantation such as closure of septal defects, repair of the tricuspid valve, or ligation of the left atrium due to atrial fibrillation [9]. The classical implant operation through median sternotomy also involves the use of the heart-lung machine; the operation is divided into three main steps:…”

Section: Indication and Standard Approachmentioning

confidence: 99%

Minimally Invasive Ventricular Assist Device Surgery

Comisso¹,

Montalto²,

Nicolò³

et al. 2020

Cardiac Surgery Procedures

View full text Add to dashboard Cite

Heart failure is a growing disease that affects millions of people around the world. Heart transplantation is currently the therapy of choice for these patients. However, the lack of donors has forced the physician to evolve another kind of therapy such as ventricular assist device (VAD) as a bridge to transplant to compensate the lack of organs. Ventricular assist devices are today a successful therapy for the treatment of heart failure; the evolution of these devices and their progressive miniaturization have allowed an evolution of their implantation technique. To date, therefore, in addition to the traditional implant through sternotomy, there are more mini-invasive implant techniques. The purpose of the treaty is to describe these techniques, the implantation sites, and the benefits they can bring to patients.

show abstract

Implantation of left ventricular assist device in a patient with left ventricular non-compaction

Cited by 6 publications

References 8 publications

Usefulness of a left ventricular assist device in patients with left ventricular noncompaction

Usefulness of a left ventricular assist device in patients with left ventricular noncompaction

State-of-the art review: Noncompaction cardiomyopathy in pediatric patients

Minimally Invasive Ventricular Assist Device Surgery

Contact Info

Product

Resources

About