“…The majority of included studies were randomized controlled trials [27–45] and (cluster‐)randomized controlled trials [26,46–83], with nine controlled before‐and‐after studies [84–92], and one controlled clinical trial [93] (Tables S1 and S2). Studies were mostly conducted in the United States (n = 26) [28,31,32,35–40,44,45,51,52,55,57,58, 60,64,65,68,69,73,75,82,83,93], UK (n = 14) [27,29,34,42,46, 47,54,61,67,74,77,78,81,92] and The Netherlands (n = 11) [30,43,49,63,66,70,79,84,86,89,91]. Settings were PC practices or general practices, although 20 (PC or general medicine) clinics [28,31,36–38,41,44,45,50,52,55,57,58,64,72,76,87,88,93] and two studies on collaboration between hospitals/clinics and PC [32,33] were included as well.…”