Implementation and outcomes of a pharmacist-led collaborative drug therapy management program for oncology symptom management

Homan, Morgan J; Reid, Justin H; Nachar, Victoria R; Benitez, Lydia; Brown, Anna M.; Kraft, Shawna; Hough, Shannon; Christen, Catherine; Frame, David; McDevitt, Rachel L

doi:10.1007/s00520-021-06239-0

Cited by 11 publications

(10 citation statements)

References 12 publications

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“…However, interventions made by the clinical pharmacists were based on consultations for select patients in the outpatient oncology clinic. Another study 7 demonstrated that clinical pharmacists (as permitted by a CDTA program) can improve the severity of GI toxicities in referred patients with cancer in an oncology clinic. Unlike these two studies that focused on one specific symptom, our study innovatively demonstrated a proactive multidisciplinary effort in managing multiple patient-reported symptoms for all patients undergoing cancer treatments in an outpatient infusion center setting.…”

Section: Discussionmentioning

confidence: 99%

“…Although pharmacist-led interventions have shown favorable outcomes, publications for these were based on patient encounters in the inpatient setting or clinics. 7,8 The involvement of oncology clinical pharmacist (OCP) in ambulatory infusion centers to improve efficiency, quality of care, and safety of patients with cancer is yet to be characterized. Recognizing that a significant waiting time for symptom evaluations may adversely affect patients' clinical outcome and influences patients' perception about the quality of care he/she received, the clinical teams at two infusion centers of our health system implemented a TRAE detection and reduction program aimed at recognizing and managing these symptoms early, with the goal of improving patient care, preventing unwanted toxicities, and enabling patients to complete their course of treatments.…”

Section: Introductionmentioning

confidence: 99%

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Optimizing Multidisciplinary Treatment-Related Adverse Effects Detection and Reduction in Patients Undergoing Active Cancer Treatments in Ambulatory Infusion Centers

Chung

Rome

Desai

et al. 2022

JCO Oncology Practice

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PURPOSE: The objective of this study was to describe the implementation of an interdisciplinary supportive care program for treatment-related adverse effects (TRAEs) of patients with cancer in two ambulatory infusion centers affiliated with a major health system. METHODS: A management program of TRAEs was developed on the basis of the collaboration between oncologists, infusion center oncology nurses, and a board-certified oncology clinical pharmacist for patients with cancer in two outpatient infusion centers. Patients received multidisciplinary interventions or oncologist-driven interventions on the basis of their reported symptoms during their cancer treatments. They were followed prospectively at regular intervals for further symptom management interventions. To evaluate this program, a retrospective chart review was performed, and data were collected regarding the number and nature of these TRAEs. The outcomes of their interventions were assessed up to 3 months since initial encounters. Data for patient satisfaction were also collected before and after implementation of the program. RESULTS: A total of 308 patients received 469 interventions initiated either by the multidisciplinary team or by oncologists over a 3-year period. Compared with oncologist-led interventions, multidisciplinary interventions were statistically significant in the number of interventions ( P = .004; 95% CI, 17.9 to 36.2) and in reducing occurrences of TRAEs ( P = .03; 95% CI, 33.8 to 72.4) such as dermatological toxicities, diarrhea, immune-related adverse effects, mucositis, and nausea or vomiting after 1-month follow-up. Multidisciplinary team captured approximately 40% of TRAEs of all grades that were escalated to oncologists for further management, which led to an overall improvement in management of TRAEs. CONCLUSION: Multidisciplinary care for patients in infusion centers led to improvement in treatment-related toxicities.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Optimizing Multidisciplinary Treatment-Related Adverse Effects Detection and Reduction in Patients Undergoing Active Cancer Treatments in Ambulatory Infusion Centers

Chung

Rome

Desai

et al. 2022

JCO Oncology Practice

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“…drug-drug and drug-disease interactions, and providing patient education on medications. [37][38][39][40][41][42][43][44][45][46][47] Several studies have shown that clinical pharmacist involvement in the cancer care process resulted in better patient satisfaction and enhanced control of side effect profiles overall. 40,43,44,48 These findings infer that pharmacists are positioned to help alleviate usage disparities with supportive care medications in patients with cancer.…”

Section: Discussionmentioning

confidence: 99%

A scoping review on the relationship between race/ethnicity and the receipt of supportive care medications during cancer treatment: Implications for the clinical pharmacist

Awunti

DeRemer

Rogers

et al. 2022

J Am Coll Clin Pharm

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There is surmounting levels of evidence on the health disparities within cancer treatment in the United States (US). Most of the research focused on cancer specific factors including anticancer incidence, screening, treatment and follow‐up, and clinical outcomes such as overall survival (OS). Less is known about the disparities present with supportive care medication use in cancer patients. Supportive care utilization during cancer treatment has been linked to improved quality of life (QoL) and OS among patients. The goal of this scoping review is to summarize findings of current literature on the relationship between race and ethnicity and the receipt of supportive care medications during cancer treatment for pain and chemotherapy‐induced nausea and vomiting (CINV). This scoping review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta‐Analysis (PRISMA‐ScR) guidelines. Our literature search included quantitative studies, qualitative studies, and grey literature written in the English language with clinically relevant outcomes pertaining to pain and CINV management in cancer treatment published from 2001 to 2021. Articles that met the predefined inclusion criteria were considered for inclusion in the analysis. The initial search yielded 308 studies. Following deduplication and screening, 14 studies met the predefined inclusion criteria, with majority of the studies being quantitative studies (n = 13). Collectively, results were mixed results regarding the presence of racial disparities for supportive care medication use. Half of the studies (n = 7) supported this finding whereas, the other half (n = 7) did not identify any racial disparities. In our review, multiple studies illustrate the existence of disparities in the use of supportive care medications in some cancer types. Clinical pharmacists should strive to eliminate supportive medication use disparities as part of a multidisciplinary team. In order to develop strategies to prevent supportive care medication use disparities in this population, further research and analysis of external factors that influence them are needed.

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“…Their complex journey makes it possible to provide services and information that ensure the effectiveness and appropriateness of treatment, patient safety and cost optimization. 14 As mistake-related AEs during the medication management process were the most frequent cause of harm to patients during hospitalization, 15,16 the impact of pharmacists' proximity to HCPs on reducing these events is well recognized by the literature 17 and by the Italian Ministry of Health. 18 Our survey showed a good level of collaboration between HSCT HCPs and pharmacists, who seemed to be actively involved in transplant activities.…”

Section: Discussionmentioning

confidence: 99%

The role of pharmacies in haematopoietic stem cell transplantation process: A nationwide survey by Gruppo Italiano Trapianto di Midollo Osseo

et al. 2021

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Implementation and outcomes of a pharmacist-led collaborative drug therapy management program for oncology symptom management

Cited by 11 publications

References 12 publications

Optimizing Multidisciplinary Treatment-Related Adverse Effects Detection and Reduction in Patients Undergoing Active Cancer Treatments in Ambulatory Infusion Centers

Optimizing Multidisciplinary Treatment-Related Adverse Effects Detection and Reduction in Patients Undergoing Active Cancer Treatments in Ambulatory Infusion Centers

A scoping review on the relationship between race/ethnicity and the receipt of supportive care medications during cancer treatment: Implications for the clinical pharmacist

The role of pharmacies in haematopoietic stem cell transplantation process: A nationwide survey by Gruppo Italiano Trapianto di Midollo Osseo

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