Within the context of semiquantum nonlocal games, the trust can be removed from the measurement devices in an entanglement-detection procedure. Here, we show that a similar approach can be taken to quantify the amount of entanglement. To be specific, first, we show that in this context, a small subset of semiquantum nonlocal games is necessary and sufficient for entanglement detection in the local operations and classical communication paradigm. Second, we prove that the maximum payoff for these games is a universal measure of entanglement which is convex and continuous. Third, we show that for the quantification of negative-partial-transpose entanglement, this subset can be further reduced down to a single arbitrary element. Importantly, our measure is measurement device independent by construction and operationally accessible. Finally, our approach straightforwardly extends to quantify the entanglement within any partitioning of multipartite quantum states. DOI: 10.1103/PhysRevLett.118.150505 Introduction.-Entanglement is a valuable resource for practical as well as fundamental applications of quantum theory, ranging from quantum computation and communication to metrology [1-3]. There are two major challenges in understanding entanglement that stimulates this research. First, it is extremely difficult to specify all the nonentangled bipartite or multipartite quantum states. In fact, the problem is known to be NP-hard [4,5]. Second, not surprisingly, the characterization of entangled states, i.e., the quantification of entanglement within quantum states, is an equally difficult task. The answer to the second challenge is practically very important because it tells us how well our protocols will perform using a given state [6][7][8][9].Focusing on the second challenge above, a first level of hardness is that the quantification of entanglement using almost any entanglement measure, e.g., entanglement of formation [10], negativity [11,12], or random robustness [13], requires estimating a large number of density matrix elements, a task which is difficult to perform on bipartite and multipartite quantum states. While this difficulty can be partially circumvented by making use of entanglement witnesses (EWs) when lower bounds on the entanglement are desired [14][15][16][17][18][19], errors and misalignments of the measurement devices can still lead to incorrect estimations of the quantities and thus, erroneous conclusions. A measurementdevice-independent approach is therefore desirable.Recent work by Buscemi [20] has introduced a new way to think about entanglement detection [21][22][23][24]. The idea is to map the problem onto a modified class of nonlocal games, called semiquantum nonlocal games (SQNLGs). In any such game, two players (Alice and Bob) share a possibly entangled state. A referee (Charlie) starts by asking them