Implementation of a targeted mastitis therapy concept using an on‐farm rapid test: antimicrobial consumption, cure rates and compliance

Schmenger, Anne; Leimbach, Stefanie; Wente, Nicole; Zhang, Yanchao; Biggs, Andrew Martin; Kroemker, Volker

doi:10.1136/vr.105674

Cited by 17 publications

(22 citation statements)

References 54 publications

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“…The UK dairy industry has recently seen a rise of 9 per cent in total AMU,6 so studies aimed at reducing use are welcome. To this end, the study by Schmenger and colleagues,12 summarised on p 401 of this issue of Vet Record , is an important addition to our knowledge.…”

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confidence: 98%

“…The authors analysed bacteriological and cytological cures, as well as new infection rates and relapse rates at the quarter level. Various animal-based parameters, such as a mastitis score, age, lactation and production, were also recorded to identify ‘treatment worthy’ cows 12…”

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confidence: 99%

“…A strength of Schmenger and colleagues’ study12 was the training provided for farmers on how to use and interpret the OFC test and the continued support offered by the veterinarians. Farmers had a say in the construction of the protocols to ensure they were as practical as possible (eg, data entry was ordered in a particular way to help farmers with treatment decisions and paperwork), and they were trusted to implement the testing regime on their own without continual supervision.…”

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confidence: 99%

“…In cows with lower mastitis scores, local antimicrobial treatment was administered if the results of the OFC indicated a Gram‐positive pathogen and the cow fell into the ‘treatment‐worthy’ category. Only anti‐inflammatories were given immediately on detection of a case of clinical mastitis, as treatment with antimicrobials was delayed until the results of the OFC were known 12 …”

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confidence: 99%

“…However, despite this support, the farmers frequently strayed from the recommended treatment protocols, and this resulted in a separate study group called the tLCTmod 12. This group had relatively more mild mastitis cases that they treated with antibiotics, contrary to the recommendations.…”

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confidence: 99%

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Developing targeted antimicrobial treatment protocols for mastitis

Morgans

2020

Veterinary Record

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confidence: 98%

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confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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confidence: 99%

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Developing targeted antimicrobial treatment protocols for mastitis

Morgans

2020

Veterinary Record

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Factors influencing Scottish dairy farmers’ antibiotic use

et al. 2023

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Background Good stewardship of antibiotics can reduce the development and impact of antimicrobial resistance (AMR); therefore, understanding farmers’ antibiotic use is of interest to stakeholders. To date, few qualitative studies have looked at farmers’ antibiotic use on dairy farms in the UK. Methods Semi‐structured interviews were used to explore 15 Scottish dairy farmers’ antibiotic use behaviours and the factors influencing their antibiotic use on farms. Results Using an inductive process, the results from the interviews were analysed, and four key themes were extracted: use of antibiotics, awareness of AMR, determinants of antibiotic use and future aspirations. Limitations Some of the farmers interviewed were wary about discussing their antibiotic use, which could mean that some contentious issues were not discussed. The farmers also all belonged to a single milk‐buying group, which may limit the generalisability of the findings. Conclusions The quantities of antibiotics used were felt to be driven by the disease prevalence on farms, cows being indoors more, increasing herd sizes resulting in increased stocking densities, retention of poorer cows and substandard housing. Farmer knowledge of antibiotics varied, and not all farmers interviewed were aware of AMR. The farm veterinarian, the press and peers were found to be the main sources of antibiotic information.

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Potential of ESBL-producing Escherichia coli selection in bovine feces after intramammary administration of first generation cephalosporins using in vitro experiments

Speksnijder

Hopman

Kusters

et al. 2022

Sci Rep

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Selection and spread of Extended Spectrum Beta-Lactamase (ESBL) -producing Enterobacteriaceae within animal production systems and potential spillover to humans is a major concern. Intramammary treatment of dairy cows with first-generation cephalosporins is a common practice and potentially selects for ESBL-producing Enterobacteriaceae, although it is unknown whether this really occurs in the bovine fecal environment. We aimed to study the potential effects of intramammary application of cephapirin (CP) and cefalonium (CL) to select for ESBL-producing Escherichia coli in the intestinal content of treated dairy cows and in manure slurry, using in vitro competition experiments with ESBL and non-ESBL E. coli isolates. No selection of ESBL-producing E. coli was observed at or below concentrations of 0.8 µg/ml and 4.0 µg/ml in bovine feces for CP and CL, respectively, and at or below 8.0 µg/ml and 4.0 µg/ml, respectively, in manure slurry. We calculated that the maximum concentration of CP and CL after intramammary treatment with commercial products will not exceed 0.29 µg/ml in feces and 0.03 µg/ml in manure slurry. Therefore, the results of this study did not find evidence supporting the selection of ESBL-producing E. coli in bovine feces or in manure slurry after intramammary use of commercial CP or CL-containing products.

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Implementation of a targeted mastitis therapy concept using an on‐farm rapid test: antimicrobial consumption, cure rates and compliance

Cited by 17 publications

References 54 publications

Developing targeted antimicrobial treatment protocols for mastitis

Developing targeted antimicrobial treatment protocols for mastitis

Factors influencing Scottish dairy farmers’ antibiotic use

Potential of ESBL-producing Escherichia coli selection in bovine feces after intramammary administration of first generation cephalosporins using in vitro experiments

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