This systematic literature review provides information on the use of mixed
methods research in human factors and ergonomics (HFE) research in health care. Using the
PRISMA methodology, we searched four databases (PubMed, PsycInfo, Web of Science, and
Engineering Village) for studies that met the following inclusion criteria: (1) field
study in health care, (2) mixing of qualitative and quantitative data, (3) HFE issues, and
(4) empirical evidence. Using an iterative and collaborative process supported by a
structured data collection form, the six authors identified a total of 58 studies that
primarily address HFE issues in health information technology (e.g., usability) and in the
work of healthcare workers. About two-thirds of the mixed methods studies used the
convergent parallel study design where quantitative and qualitative data were collected
simultaneously. A variety of methods were used for collecting data, including interview,
survey and observation. The most frequent combination involved interview for qualitative
data and survey for quantitative data. The use of mixed methods in healthcare HFE research
has increased over time. However, increasing attention should be paid to the formal
literature on mixed methods research to enhance the depth and breadth of this
research.