Tuning of the required torque and the shift pattern has been made in cruise driving manually by many engineers in the past. However, manual tuning has the disadvantages of high cost and time consumption for the operator. This paper studies the driving simulation and auto-tuning of the required torque and shift pattern. The target vehicle is a vehicle operated by an engine with the function of speed tracking. First, the power train simulator which was verified by the actual driving, was made in MATLAB. Then, driving simulation was conducted by the powertrain simulator and auto-tuning was also conducted by driving data. Tuning of the required torque means calibration of values of the required acceleration function, and tuning of shift pattern means the calibration of lines of up or downshift. The modified parameters are re-applied to the vehicle which is driven in the virtual environment. This process is repeated until the required performance has been achieved. It is a feedback process to get solutions of the parameters for a given vehicle load. Consequently, engineers can automatically tune parameters instead of manually tuning the parameters, which can satisfy vehicle performance, as well as increase the comfort feel for the driver.