Changes over the years require adaptation to thrive in today’s academic and professional scenarios. Teachers of future healthcare professionals face new challenges daily, like artificial intelligence and its impact on learning, helping young students to keep focused, using the best available data and good teaching/learning resources, making evidence-based decisions. As new demands arise, some of the old ones are still present, challenging students, teachers, and professionals. When it comes to medical education, learning how to deal with professional’s mental health is still an issue. This chapter aims to discuss strategies to improve physicians and medical students ‘abilities to cope with stress and mental health issues, and its impacts on their life and on the lives of their patients and families.