2022
DOI: 10.1038/s41371-022-00713-w
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Implementation of the 2018 ESC/ESH Guidelines for the management of hypertension in primary care: the HYPEDIA study

Abstract: The HYPEDIA study aimed at evaluating the implementation of the 2018 European guidelines for treating hypertension in primary care. A nationwide prospective non-interventional cross-sectional study was performed in consecutive untreated or treated hypertensives recruited mainly in primary care in Greece. Participants’ characteristics, office blood pressure (BP) (triplicate automated measurements, Microlife BPA3 PC) and treatment changes were recorded on a cloud platform. A total of 3,122 patients (mean age 64 … Show more

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Cited by 3 publications
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“…Besides patient-related factors such as non-adherence, the reasons for uncontrolled BP are manifold, including irregular supply of antihypertensive drugs with frequent changes in prescriptions (and hence reduced adherence), substandard quality of drugs, shortage of health workers and centers, and poverty in general [ 60 , 61 ]. In addition, physician inertia is a well-known phenomenon in the case of treated, but uncontrolled hypertension [ 62 ]. The same phenomenon has been observed for treating clinical officers and nurses in the present LighTen Study with its low rate (13%) of treatment adjustments in patients with BP ≥ 140/90 mmHg during patient visits.…”
Section: Discussionmentioning
confidence: 99%
“…Besides patient-related factors such as non-adherence, the reasons for uncontrolled BP are manifold, including irregular supply of antihypertensive drugs with frequent changes in prescriptions (and hence reduced adherence), substandard quality of drugs, shortage of health workers and centers, and poverty in general [ 60 , 61 ]. In addition, physician inertia is a well-known phenomenon in the case of treated, but uncontrolled hypertension [ 62 ]. The same phenomenon has been observed for treating clinical officers and nurses in the present LighTen Study with its low rate (13%) of treatment adjustments in patients with BP ≥ 140/90 mmHg during patient visits.…”
Section: Discussionmentioning
confidence: 99%
“…BMI was obtained by calculating the participant’s weight divided by the square of their height (kg/m 2 ). We defined hypertension as a systolic blood pressure ≥140 mmHg and/or a diastolic blood pressure ≥90 mmHg in at least two clinic blood pressure measurements on different days ( Kollias et al, 2022 ). We defined smoking as currently or previously smoking, and drinking was defined as drinking alcohol at least once a week for at least a year ( Xie et al, 2010 ).…”
Section: Methodsmentioning
confidence: 99%
“…As guidelines have assessed, renin–angiotensin system blockers (angiotensin-converting enzyme or ACEI/angiotensin II receptor antagonists such as, ARAII) are recommended in the first step of pharmacological treatment. This is supported by the strong evidence of cardiovascular and renal protection with these drug classes [ 11 ]. Therefore, these antihypertensives have a theoretical increase in COVID-19 mortality because of their inducible effect on the expression of angiotensin-converting enzyme II (ACEII), the known functional receptor utilized by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [ 12 ].…”
Section: Introductionmentioning
confidence: 91%