Implication of Margin of Glottic Cancer: Laser Surgery

Abstract

Background and ObjectivesAn involved resection margin in a head and neck malignant neoplasm is one of the most important factors affecting local recurrence. The aim of this study is to assess the clinical impact of resected margin status in laser surgery for glottic cancers on local recurrences and larynx preservation. Materials and MethodsSixty four patients of glottis cancer from January 1994 to December 2013 were included in this study. The records were evaluated for disease recurrence rate, follow up duration, additional treatment modality, and laryngeal preservation. Pathologic reports with resection margin status were reviewed in all cases. Resection margins were evaluated in anterior, posterior, superior, inferior, and deep directions. ResultsLocal recurrence was not associated with positive mucosal margin. The number of positive margins was also not associated with local recurrence (p=0.24). Only deep margin status showed association with local recurrence (p<0.05). The laryngeal preservation rate was 97%. All patients who underwent salvage laryngectomy had a positive deep margin. ConclusionUnlike other studies, in this study, mucosal margin did not have a significant impact on clinical outcome in laser surgery for early glottic cancer. However, a deep margin should be carefully evaluated during surgery and more study is needed.

Recurrent Glottic Cancer Treated with Carbon Dioxide Laser: A Case Report

“…Glottic cancer is easy to detect because of the early onset of symptoms, such as hoarseness, and has a good prognosis owing to low lymph node metastasis and remote transfer. [1][2][3] Preserving the larynx's physiological functions, such as voice and swallowing, in the treatment of glottic cancer is considered important for the complete cure of the disease. Radiation therapy, open partial laryngectomy, and cordectomy are performed as treatments for glottic cancer, and the therapeutic performance of such methods are reportedly similar.…”