Ou MC decrescendo phenomenon treatment (OuDPt) reduces pain or inflammation in an area by placing the contralateral hand over the lesion. OuDPt has been shown to have an anticancer effect, which may be due to tissue function normalization. Four cases of cancers that were treated with OuDPt were reported in this study. In two patients who received only OuDPt for anticancer treatment, one patient with stage IIIB uterine endometrial cancer and another with stage IVA ovarian cancer, the cancers regressed but later resumed growth despite continuing OuDPt. Another case of stage II uterine endometrioid adenocarcinoma showed prominent tumour regression after 8 months of OuDPt. After the initial tumour regression, the patient seldom performed OuDPt and the tumour resumed growth. The other case, stage III pancreatic cancer, showed decreasing levels of CA199 after combining OuDPt with chemotherapy. The resumed growth of this advanced cancer despite OuDPt may be due to poor accessibility of the tumour or escaping phenomenon through an unknown mechanism. Nonetheless, OuDPt shows a cancer suppression effect and can be performed by patients, which suggests that this therapy may be availed as a method of cancer prevention. Further study is warranted.