The construction of a precast flat plate frame of buildings is considered for its implementation during the restoration of the housing stock of Ukraine. The analysis of the precast flat plate floor system of the frame structural system by using the yield line method showed that in the ultimate state the floor is divided into separate discs along the joints of precast plates. This makes it possible to determine the load-bearing capacity of the floor by considering each plate taking into account their supporting and loading conditions. Based on this, experimental tests of three full-size over-columned plates of a precast flat plate floor system are carried out, according to the diagram closest to the actual scheme of their operation as part of the floor. The general deflections of the plates, moments of crack formation and width of their opening, as well as strains of concrete and reinforcement in characteristic cross-sections of the plates are determined. Based on the experimental tests, the accepted failure scheme of the over-columned plates of the precast flat plate floor system is confirmed and the feasibility of applying the yield line method to the calculation of their bearing capacity is proven.