Implications of colonic and extra-colonic findings on CT colonography in FIT positive patients in the Dutch bowel cancer screening program

Lammertink, Marieke H A; Huisman, Jelle F.; Bernsen, Marie Louise E.; Niekel, Ronald; Westreenen, Henderik L. van; Cappel, Wouter H. de Vos tot Nederveen; Spanier, B.W.M.

doi:10.1080/00365521.2021.1966091

Cited by 2 publications

(2 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although most of these unexpected anomalies are unlikely to be clinically relevant, many require further investigation or follow‐up and can result in unnecessary treatments, anxiety for patients and physicians and increased healthcare costs. 18 , 19 An earlier study reported an incidental finding rate of 16% on radiological staging in patients with stage I‐IV CRC. 20 The risk of detecting these findings should be discussed during an informed consent procedure prior to imaging.…”

Section: Introductionmentioning

confidence: 99%

“…Radiological imaging can lead to the discovery of unexpected extra‐colonic incidental findings. Although most of these unexpected anomalies are unlikely to be clinically relevant, many require further investigation or follow‐up and can result in unnecessary treatments, anxiety for patients and physicians and increased healthcare costs 18,19 . An earlier study reported an incidental finding rate of 16% on radiological staging in patients with stage I‐IV CRC 20 .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Diagnostic value of radiological staging and surveillance for T1 colorectal carcinomas: A multicenter cohort study

et al. 2023

Self Cite

View full text Add to dashboard Cite

Background The role of radiological staging and surveillance imaging is under debate for T1 colorectal cancer (CRC) as the risk of distant metastases is low and imaging may lead to the detection of incidental findings. Objective The aim of this study was to evaluate the yield of radiological staging and surveillance imaging for T1 CRC. Methods In this retrospective multicenter cohort study, all patients of 10 Dutch hospitals with histologically proven T1 CRC who underwent radiological staging in the period 2000–2014 were included. Clinical characteristics, pathological, endoscopic, surgical and imaging reports at baseline and during follow‐up were recorded and analyzed. Patients were classified as high‐risk T1 CRC if at least one of the histological risk factors (lymphovascular invasion, poor tumor differentiation, deep submucosal invasion or positive resection margins) was present and as low‐risk when all risk factors were absent. Results Of the 628 included patients, 3 (0.5%) had synchronous distant metastases, 13 (2.1%) malignant incidental findings and 129 (20.5%) benign incidental findings at baseline staging. Radiological surveillance was performed among 336 (53.5%) patients. The 5‐year cumulative incidence of distant recurrence, malignant and benign incidental findings were 2.4% (95% confidence interval (CI): 1.1%–5.4%), 2.5% (95% CI: 0.6%–10.4%) and 18.3% (95% CI: 13.4%–24.7%), respectively. No distant metastatic events occurred among low‐risk T1 CRC patients. Conclusion The risk of synchronous distant metastases and distant recurrence in T1 CRC is low, while there is a substantial risk of detecting incidental findings. Radiological staging seems unnecessary prior to local excision of suspected T1 CRC and after local excision of low‐risk T1 CRC. Radiological surveillance should not be performed in patients with low‐risk T1 CRC.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Diagnostic value of radiological staging and surveillance for T1 colorectal carcinomas: A multicenter cohort study

et al. 2023

Self Cite

View full text Add to dashboard Cite

show abstract

CT-Kolonographie

2023

View full text Add to dashboard Cite

Zusammenfassung Hintergrund Um mit der CT-Kolonographie (CTK) gute Ergebnisse zu erzielen, ist neben der spezifischen radiologischen Expertise eine hochqualitative Durchführung der Untersuchung und eine Indikationsstellung gemäß fachspezifischen Richtlinien erforderlich. Ziel der Arbeit Ziel dieser Arbeit ist es, einen Überblick über aktuelle Standards der Untersuchungstechnik sowie über Indikationen und Kontraindikationen der CTK in Anlehnung an rezente Empfehlungen und Richtlinien zu geben. Material und Methoden Mittels einer ausführlichen Literaturrecherche wird der aktuelle Wissensstand zur Untersuchungstechnik sowie zu den Einsatzgebieten und den Kontraindikationen zur CTK zusammengefasst. Ergebnisse Die CTK ist die radiologische Untersuchung der Wahl zur Detektion kolorektaler Neoplasien. Indikationen sind die unvollständige Koloskopie, Kontraindikationen oder Ablehnung der Koloskopie und die opportunistische Dickdarmkrebsvorsorge. Die Untersuchungstechnik umfasst eine den speziellen Erfordernissen der CTK angepasste Darmvorbereitung einschließlich „fecal tagging“, die Darmdistension, einen Niedrigdosis-CT-Scan in zwei Patientenpositionen sowie eine kombinierte 2D- und 3D-Auswertung. Diskussion Die Durchführung der CTK nach aktuellen technischen Standards ist Voraussetzung für hochqualitative und aussagekräftige Untersuchungen und damit auch ein Schlüsselfaktor zur korrekten Diagnosefindung. Als nichtinvasive Untersuchungsoption ermöglicht sie bei vielen Indikationen klinisch relevante Ergebnisse.

show abstract

Implications of colonic and extra-colonic findings on CT colonography in FIT positive patients in the Dutch bowel cancer screening program

Cited by 2 publications

References 15 publications

Diagnostic value of radiological staging and surveillance for T1 colorectal carcinomas: A multicenter cohort study

Diagnostic value of radiological staging and surveillance for T1 colorectal carcinomas: A multicenter cohort study

CT-Kolonographie

Contact Info

Product

Resources

About