Implications of long-term exposure of a Lymantria dispar L. population to pollution for the response of larval midgut proteases and acid phosphatases to chronic cadmium treatment

Matić, Dragana; Vlahović, Milena; Ilijin, Larisa; Grčić, Anja; Filipović, Aleksandra; Todorović, Dajana; Perić-Mataruga, Vesna

doi:10.1016/j.cbpc.2021.109172

Cited by 4 publications

(2 citation statements)

References 56 publications

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“…Another aspect of heavy metals is their negative impact on macromolecular chemicals in any organism that is exposed to them (Violante et al, 2010). The Alp and ACP can be considered in this L. dispar larvae (Mati c et al, 2021). In our findings, an increasing activity trend was observed in both of these compounds initially; however, after long exposure, that is, after the third generation, the decreasing activity was evident.…”

Section: Discussionsupporting

confidence: 48%

“…These two enzymes play a vital role in supporting, modulating, accelerating phagocytosis, transporting nutrients and digesting those (Karthi et al, 2018). The Cd may change the activity of Alp and ACP in the midgut cells of lepidopterans and it has been shown that Cd enhanced the ACP activity in the midgut of L. dispar larvae (Matić et al, 2021). In our findings, an increasing activity trend was observed in both of these compounds initially; however, after long exposure, that is, after the third generation, the decreasing activity was evident.…”

Section: Discussionmentioning

confidence: 99%

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Responses of continuous cadmium exposure on some biological and physiological performance of cotton bollworm Helicoverpa armigera

Azizi,

Jalali Sendi

2024

Physiological Entomology

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A detailed effect of continuous exposure of Cd on an important pest of crops like Helicoverpa armigera is lacking in the current literature. The cadmium was provisioned at 1.25, 2.5 and 5 mg/kg in the artificial diet and fed to newly hatched larvae for at least three subsequent generations. The total developmental period and fecundity were severely affected with no larval hatching in treated insects. Total haemocyte count and differential haemocyte count (i.e., granulocytes and plasmatocytes) were decreased significantly compared to controls in treated insects. The antioxidant system (i.e., catalase, glucose‐6‐phosphate dehydrogenase, superoxide dismutase and peroxidase), and the two detoxifying agents glutathione‐s‐transferase showed increased activity compared to controls. The results of the acetylcholinesterase assay showed a decrease in activity. Increased rate of aspartate aminotransferase, alanine aminotransferase, uric acid and decreased rate of alkaline phosphatase and lactate dehydrogenase in the first generation but showing an increasing trend in next two generations. The acid phosphatase activity was increased in the first two generations but significantly reduced in the third generation. The discrepancy in all physiological activities corresponded with the histological study of midgut infrastructure. It is inferred from the obtained results that cadmium continuous exposure affects every system of any organism that may perform irreparable damages.

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Section: Discussionsupporting

confidence: 48%

Section: Discussionmentioning

confidence: 99%

Responses of continuous cadmium exposure on some biological and physiological performance of cotton bollworm Helicoverpa armigera

Azizi,

Jalali Sendi

2024

Physiological Entomology

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Dietary Lipids and Their Metabolism in the Midgut

Delamotte,

Montagne

2024

Advances in Experimental Medicine and Biology

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Exploration of Response Mechanisms in the Gills of Pacific Oyster (Crassostrea gigas) to Cadmium Exposure through Integrative Metabolomic and Transcriptomic Analyses

Dong,

Sun,

Chu

et al. 2024

Animals

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Marine mollusks, including oysters, are highly tolerant to high levels of cadmium (Cd), but the molecular mechanisms underlying their molecular response to acute Cd exposure remain unclear. In this study, the Pacific oyster Crassostrea gigas was used as a biological model, exposed to acute Cd stress for 96 h. Transcriptomic analyses of their gills were performed, and metabolomic analyses further validated these results. In our study, a total of 111 differentially expressed metabolites (DEMs) and 2108 differentially expressed genes (DEGs) were identified under acute Cd exposure. Further analyses revealed alterations in key genes and metabolic pathways associated with heavy metal stress response. Cd exposure triggered physiological and metabolic responses in oysters, including enhanced oxidative stress and disturbances in energy metabolism, and these changes revealed the biological response of oysters to acute Cd stress. Moreover, oysters could effectively enhance the tolerance and detoxification ability to acute Cd exposure through activating ABC transporters, enhancing glutathione metabolism and sulfur relay system in gill cells, and regulating energy metabolism. This study reveals the molecular mechanism of acute Cd stress in oysters and explores the molecular mechanism of high tolerance to Cd in oysters by using combined metabolomics and transcriptome analysis.

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Implications of long-term exposure of a Lymantria dispar L. population to pollution for the response of larval midgut proteases and acid phosphatases to chronic cadmium treatment

Cited by 4 publications

References 56 publications

Responses of continuous cadmium exposure on some biological and physiological performance of cotton bollworm Helicoverpa armigera

Responses of continuous cadmium exposure on some biological and physiological performance of cotton bollworm Helicoverpa armigera

Dietary Lipids and Their Metabolism in the Midgut

Exploration of Response Mechanisms in the Gills of Pacific Oyster (Crassostrea gigas) to Cadmium Exposure through Integrative Metabolomic and Transcriptomic Analyses

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