Implications of pars planitis-associated cystoid macular edema on visual outcome and management in children

Navarrete, Ana; Koriat, Adi; Amer, Radgonde

doi:10.1007/s00417-020-04696-7

Cited by 9 publications

(5 citation statements)

References 25 publications

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“…We have recently published a cohort of 33 children (58 eyes) with pars-planitis in whom ERD occurred in 7% of the eyes [ 2 ]. None of them had ERD at presentation but developed it during the follow-up time.…”

Section: Discussionmentioning

confidence: 99%

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Total exudative retinal detachment in a child with pars planitis- a challenging case with optimistic results

Navarrete

Jaouni

Amer

2023

J Ophthal Inflamm Infect

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We describe a case report of pediatric pars planitis complicated with massive exudative retinal detachment (ERD). A 7-year-old presented with visual acuity (VA) in the right eye (RE) of 6/9 and in the left eye (LE) 6/15. Fundoscopy revealed BE inferior retinoschisis, vitritis and snowballs. He was treated with systemic immunosuppressants. RE retinoschisis resolved within 2 months. Three years later presented with LE VA 6/60 and total ERD. Systemic and intravitreal steroids were administered. Due to refractoriness, he underwent 360° scleral buckle and drainage of subretinal fluid. No retinal breaks or traction were detected. Five months postoperatively LE VA was 6/7.5. Long-term stable outcome was maintained. We report a challenging total ERD as a complication of pars planitis. Although extensive and non-responsive to medical therapy, complete resolution and improvement in vision was achieved with surgical intervention and systemic immunosuppression. We speculate that uncontrolled chronic vasculitic process culminated in diffuse ERD.

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Section: Discussionmentioning

confidence: 99%

“…Retinal detachment (RD) is an uncommon complication of pars planitis (PP), reported in up to 10% of the cases [1][2][3]. PP is characterized by chronic inflammation in the pars plana.…”

Section: Introductionmentioning

confidence: 99%

Total exudative retinal detachment in a child with pars planitis- a challenging case with optimistic results

Navarrete

Jaouni

Amer

2023

J Ophthal Inflamm Infect

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“…The use of OCT as a screening tool has been proposed for the initial work-up of children with pars planitis to identify possible CME and inform disease management and visual prognosis. 53 In a recent study of patients with pars planitis presenting at mean age of 14.3 ± 10.5 years, using SD-OCT, Yalçındagˇ et al 54 found that the presence of diffuse CME and loss of normal foveal contour were predictive of poor visual acuity. In monitoring treatment response, SD-OCT may show decreased vitreous punctate spots, indicative of vitreous cells ( Figure 3 ) and CME.…”

Section: Imaging In Pediatric Uveitismentioning

confidence: 99%

“…In monitoring treatment response, SD-OCT may show decreased vitreous punctate spots, indicative of vitreous cells ( Figure 3 ) and CME. 53 , 55 , 56 …”

Section: Imaging In Pediatric Uveitismentioning

confidence: 99%

Multimodal imaging in pediatric uveitis

et al. 2021

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Pediatric uveitis accounts for up to 10% of all uveitis cases, so special attention must be paid to ensure early diagnosis as well as treatment and follow-up of these young patients in order to decrease the risk of possible ocular complications and consequently vision loss. Multimodal imaging has been an effective and important adjunct in the diagnoses and management of uveitis, especially in children. Reviewed here are the currently utilized modalities, advances, as well as their applications in juvenile idiopathic arthritis–associated uveitis, pars planitis, retinal vasculitis, tubulointerstitial nephritis and uveitis syndrome, Behçet disease, Blau syndrome, and Vogt–Koyanagi–Harada syndrome.

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“…Заболевание характеризуется длительным, многолетним течением и скудными клиническими проявлениями, среди которых имеются и сходные с ССГ признаки раздражения глазной поверхности [14][15][16]. Лечение ХПУ проводится с учетом формы заболевания, наличия осложнений и включает как консервативные, так и хирургические способы [17][18][19][20]. Однако особенности клинического течения и лечения ССГ на фоне ХПУ остаются недостаточно изученными.…”

Section: Introductionunclassified

Complex treatment for dry eye disease in intermediate uveitis

Tatarnikova¹,

Krivosheina²

2022

Russian Journal of Clinical Ophthalmology

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Aim: to study clinical presentations of dry eye disease (DED) in intermediate uveitis (pars planitis) and develop a complex treatment algorithm including tear substitutes, reparative, and anti-inflammatory therapies combined with laser photocoagulation. Patients and Methods: the study enrolled 98 patients divided into the study group (n=78) and the comparison group (n=20). Study group patients received complex treatment, including tear substitutes, anti-inflammatory therapies, and laser photocoagulation. Comparison group patients received topical medications only. All patients underwent a complex examination including the OSDI questionnaire, visual acuity, IOP measurements, slit lamp examination, binocular dilated fundus examination with scleral indentation, and Schirmer’s test 1 at baseline, after baseline three and six months. Treatment efficacy was assessed based on the severity of intermediate uveitis presentations. Results: intermediate uveitis exacerbates DED. The more active chorioretinal inflammation near the ora serrata is, the more severe clinical, functional changes of the ocular surface are. Complex treatment significantly improved typical DED complaints by the OSDI score (by 34.8%), ocular surface by slit-lamp examination (lower occurrence of conjunctival fold overhang, by 51.8%), mild eyelid and conjunctival hyperemia, and conjunctival discharge. Six months after treatment, a 2-fold (vs. baseline) increase in total tear secretion and resorption of vitreous exudates and retinal edema were reported in the study group. Changes in all parameters in the study group were more significant than in the comparison group. Conclusion: complex treatment algorithm (tear substitutes, reparative, and anti-inflammatory therapies combined with laser photocoagulation) provides a more rapid and stable reduction in chorioretinal inflammation near the ora serrata. It significantly improves subjective and objective DED signs compared to conventional pharmacotherapy. Keywords: dry eye disease, intermediate uveitis, laser photocoagulation, ora serrata. For citation: Tatarnikova E.B., Krivosheina O.I. Complex treatment for dry eye disease in intermediate uveitis. Russian Journal of Clinical Ophthalmology. 2022;22(1):30–35 (in Russ.). DOI: 10.32364/2311-7729-2022-22-1-30-35.

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Implications of pars planitis-associated cystoid macular edema on visual outcome and management in children

Cited by 9 publications

References 25 publications

Total exudative retinal detachment in a child with pars planitis- a challenging case with optimistic results

Total exudative retinal detachment in a child with pars planitis- a challenging case with optimistic results

Multimodal imaging in pediatric uveitis

Complex treatment for dry eye disease in intermediate uveitis

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