Importance of Diffusion-Weighted Imaging in the Diagnosis of Cystic Brain Tumors and Intracerebral Abscesses

Bink, Andrea; Gaa, Jochen; Franz, Kea; Weidauer, Stefan; Yan, Bernard; Lanfermann, H.; Seifert, Volker; Zanella, Friedhelm E.

doi:10.1055/s-2005-836478

Cited by 15 publications

(6 citation statements)

References 17 publications

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“…As there was no evidence of a mass effect or perilesional edema in our patient, the primary lesion was likely slowly expanding. The apparent diffusion coefficient of the lesion may assist in differentiating a cyst from a tumor but this was not done in our patient 18,20,21,25,45 …”

Section: Discussionmentioning

confidence: 96%

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Imaging Diagnosis — Intracranial Epidermoid Cyst in a Doberman Pinscher

Steinberg

Matiasek

Brühschwein

et al. 2007

Vet Radiology Ultrasound

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A 4-year-old Doberman Pinscher was evaluated for chronic progressive central vestibular disease and aggressiveness. A cyst-like lesion was identified in the region of the left cerebellopontine angle. The lesion was hypointense on T1-weighted and hyperintense on T2-weighted images. Differentials included an epidermoid or dermoid cyst, cystic neoplasm, and brain abscess. Hyperintensity on subsequent fluid-attenuated inversion recovery images excluded an arachnoid cyst. The histopathologic diagnosis was epidermoid cyst within the fourth ventricle.

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Section: Discussionmentioning

confidence: 96%

“…Based on the MR images epidermoid or dermoid cyst, cystic neoplasia, and brain abscess were considered 21–25 . Arachnoid cyst was considered less likely based on FLAIR images and the presence of the cyst wall.…”

Section: Case History Reportmentioning

confidence: 99%

Imaging Diagnosis — Intracranial Epidermoid Cyst in a Doberman Pinscher

Steinberg

Matiasek

Brühschwein

et al. 2007

Vet Radiology Ultrasound

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“…Of these 20 studies, three case series ( Bink et al., 2005 ; Chakravarthi et al., 2019 ; Khanna et al., 2018 ) and six retrospective studies ( Utsuki et al., 2006 ; Kaur et al., 2011 ; Jallo et al., 1997 ; Nakamura et al., 2011 ; Nakata et al., 2017 ; Roh et al., 2017 ) reported the anatomical location of cystic glioblastomas ( Supplementary Table 1 ). The frontal lobe was the most frequently affected (43%), followed by the temporal lobe (28%).…”

Section: Resultsmentioning

confidence: 99%

Cystic glioblastoma: A systematic review and meta-analysis of characteristics and outcomes

et al. 2022

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“…In MRI procedures, the apparent diffusion coefficient (APC) may be useful in differentiating GBM from brain fungal abscess. Combining diffusion tensor imaging (DTI) and dynamic susceptibility contrast perfusion-weighted imaging (DSC-PWI) provides better results in differentiating lesions from brain infections than each technique used alone [54][55][56].…”

Section: Differentiation Of Brain Tumors From Brain Infections and Abscessesmentioning

confidence: 99%

Brain tumours, brain metastases, and neuroinflammation: Insights from neuroimaging studies.

Roesler

Dini²,

Isolan³

2021

Preprint

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Brain tumors and brain metastases induce changes in brain tissue remodelling that lead to immunosuppression and trigger an inflammatory response within the tumor microenvironment. These immune and inflammatory changes can influence invasion and metastasis. Other neuroinflammatory and necrotic lesions may occur in patients with brain cancer or brain metastases as sequelae from treatment with radiotherapy. Glioblastoma (GBM) is the most aggressive primary malignant brain cancer in adults. Imaging methods such as positron-emission tomography (PET) and different magnetic resonance imaging (MRI) techniques are highly valuable for the diagnosis and therapeutic evaluation of GBM and other malignant brain tumors. However, differentiating between tumor tissue and inflamed brain tissue with imaging protocols remains a challenge. Here, we review recent advances in imaging methods that have helped to improve the specificity of primary tumor diagnosis versus evaluation of inflamed and necrotic brain lesions. We also comment on advances in differentiating metastasis from neuroinflammation processes. Recent advances include the radiosynthesis of 18F-FIMP, an L-type amino acid transporter 1 (LAT1)-specific PET probe that allows better differentiation between tumor tissue and inflammation compared to previous probes; and the combination different advanced imaging protocols with the inclusion of radiomics and machine learning algorithms.

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Importance of Diffusion-Weighted Imaging in the Diagnosis of Cystic Brain Tumors and Intracerebral Abscesses

Abstract: Diffusion-weighted imaging and calculation of ADC maps constitute a helpful tool to differentiate between cystic brain tumors and brain abscesses.

Cited by 15 publications

References 17 publications

Imaging Diagnosis — Intracranial Epidermoid Cyst in a Doberman Pinscher

Imaging Diagnosis — Intracranial Epidermoid Cyst in a Doberman Pinscher

Cystic glioblastoma: A systematic review and meta-analysis of characteristics and outcomes

Brain tumours, brain metastases, and neuroinflammation: Insights from neuroimaging studies.

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