Importance of fourth heart sound and preserved left atrial function in wild‐type transthyretin amyloidosis
Yuri Ochi,
Naohito Yamasaki,
Toru Kubo
et al.
Abstract:AimsA fourth heart sound (S4) was reported to be almost never present in patients with amyloid light‐chain cardiomyopathy. There have been no reports on S4 in patients with wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM). This study aimed to clarify the clinical implications of S4 in patients with ATTRwt‐CM.Methods and resultsSeventy‐six patients with ATTRwt‐CM (mean age: 80.4 ± 5.4 years, 68 males) who had undergone phonocardiography (PCG) were retrospectively assessed. We measured S4 amplitude on … Show more
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