Importance of Supplemental Patch Testing Beyond a Screening Series for Patients With Dermatitis

Warshaw, Erin M.; Buonomo, Michele; DeKoven, Joel G.; Pratt, Melanie D.; Reeder, Margo J.; Silverberg, Jonathan I.; Belsito, D.; Maibach, Howard I.; Atwater, Amber Reck; Houle, Marie‐Claude; Taylor, James S.; Zug, Kathryn A.; DeLeo, Vincent A.; Dunnick, Cory A.

doi:10.1001/jamadermatol.2021.4314

Cited by 7 publications

(2 citation statements)

References 56 publications

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“…These findings suggest that although the baseline series already include common allergens from a specific time period, the addition of specialty allergen series relating to personal history or work products is still necessary for a complete evaluation, to increase the success rate of identifying the culprit, and to improve management of patients' allergic contact dermatitis. 11,19 However, the other series, such as, photoallergen, corticosteroid, plastic & glue, textile, oil & cooling and shoe, which have a small positivity rate, are more of a concern. This may indicate an inadequate set of allergens, which warrants a review.…”

Section: Discussionmentioning

confidence: 99%

A 30-year Patch Testing Experience at Siriraj Dermatology

Kanokrungsee

Chaweekulrat²,

Chaiyabutr³

et al. 2023

Siriraj Med J

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Objective: To identify trends of contact allergy and patch testing amendments at the Contact Dermatitis Clinic, Department of Dermatology, Siriraj Hospital. Materials and Methods: Medical records of 6,862 patients referred to our clinic between January 1992 and December 2021for patch testing were reviewed. Results: The number of patients patch tested increased and reached a peak of 600 patients/year in 2019 before the COVID-19 pandemic. The most frequently used series was baseline, while the most used specific series was cosmetics. The overall positivity rate was 69%. The highest positivity rate was in the cosmetics series (70.2%). Nickel sulfate was the most common contact allergen found (24.2%). Conclusion: Our patch test service has been growing in the last 30 years. The series of allergens used for patch testing has been amended every few years to be up-to-date with current global trends of contact allergies. Continual surveillance of contact prevalence and periodic updating of those series are necessary to enhance our ability to detect culprit contact allergens, which could help us improve care of our patients.

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Section: Discussionmentioning

confidence: 99%

A 30-year Patch Testing Experience at Siriraj Dermatology

Kanokrungsee

Chaweekulrat²,

Chaiyabutr³

et al. 2023

Siriraj Med J

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“…14 One of the most commonly used diagnostic methods is the patch test. [15][16][17] The patch test is commonly used to evaluate allergic contact dermatitis. By making a reagent of the possible allergens and applying it to the skin, it is not only effective in assessing the severity of the allergic reaction, but also in helping the patient to detect the allergen.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Adverse Reactions of Cosmetics in Chinese Han Population in Recent Five Years

Dong,

Liu,

Liao

et al. 2023

CCID

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Background There are still some gaps in the summary and generalization of cosmetic-related adverse reaction reports. Objective The aim of this study is to summarize and analyze the occurrence of cosmetic adverse reactions in Shanghai Han population by using available survey data. Materials and Methods Collection, statistics and analysis of patients with cosmetic adverse reactions in Shanghai Huashan Hospital from 2017 to 2021. Results Among the 1004 patients, most of them (96.71%) were diagnosed as cosmetic contact dermatitis, which often occurred within 3 days of using cosmetics (51.79%). A total of 260 patients were tested with patch test, but the compliance rate was only 18.08%. Among them, 240 patients underwent additional European standard allergen tests, and positive allergens were detected in 210 cases (87.5%). Univariate analysis revealed that dosage form (emulsion and cream), age (≤25 years) and the allergic ingredients triethanolamine, rose oil, propylene glycol, thiomersal and musk ambrette are associated with the occurrence of cosmetic adverse reactions within seven days. A logit prediction model was also successfully constructed: Logit (P) = 1.710–0.796×1 + 1.185×2 −3.650X3-1.335X4. Conclusion This study complements the data reported on cosmetic adverse reactions in the Chinese Han population and suggests that in future clinical diagnosis and data collection, emphasis should be placed on patch testing, combining the patch test with cosmetic protoplast with the European standard allergen test to improve the detection rate.

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