Abstract:The 3 rd R, the refinement is receiving more and more attention. The optimazing of the auditory and olphactory environment of the laboratory animals is essential, because the environmental smells influence the behaviour and occasionally the epigenetics of mammals. According to the characteristics of the smell substances a chemical map is developed in the olphactory bulb. The vomeronasale organ (VNO) has an important role in the pheromonetransfered communication [1]. The VNO is expressing specific major histoco… Show more
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