Studies show that vitamin D status is associated to obesity but data in
Hispanic individuals is scarce. The aim of this study was to assess the
association between vitamin D status and obesity in a clinic-based sample in
Puerto Rico. We hypothesized that subjects with a higher adiposity would have a
lower vitamin D status. We extracted the following data from medical records of
a private clinic: age, gender, serum 25(OH)D levels, weight, height, and waist
circumference. BMI (kg/m2) and waist-to-height ratio were calculated
and categorized according to standard guidelines. Statistical analyses included
ANCOVA, Pearson correlations and Chi-square test. From 797 individuals (mean age
53.7±15.4y; 63.5% females), 35.6% were overweight and
43.7% obese. Mean 25(OH)D levels were 24.7±8.7 ng/mL;
5.3% had levels <12 ng/mL, 30.6% had levels 12–20
ng/mL, and 43.5% had levels 21–30 ng/mL. Mean 25(OH)D levels
were significantly higher in normal weight and overweight males compared to
obese males (p<0.05); and in overweight females compared to obese females
(p<0.05). Levels were also higher in those with low-risk compared to
high-risk of waist circumference and waist-to-height ratio (p<0.001). BMI,
waist circumference, and waist-to-height ratio were inversely correlated to
25(OH)D levels (p<0.001). A greater proportion of obese individuals
(41.4%) were vitamin D deficient or insufficient compared to the normal
weight (33.9%) and overweight individuals (30.3%) (p<0.05).
In conclusion, in this clinic-based sample of Puerto Rican adults, those with
higher BMI, WC, and WHtR had a significantly lower vitamin D status.