Importance of zinc for the human body in the aspect of zinc supplementation

Mońka, Izabela; Wiechuła, Danuta

doi:10.18794/aams/63507

Cited by 8 publications

(5 citation statements)

References 40 publications

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“…Dietary zinc deficiency affects approximately 30% of the world population [ 61 ]. In the authors’ own study of the diet of the Polish population conducted in 2000-2003, including the assessment of the zinc content, two methods of data collection were applied simultaneously: a questionnaire for the assessment of the whole-day diet from 24 hours preceding the day of data collection with the use of an interview questionnaire, and the use of household budget surveys by the Central Statistical Office.…”

Section: Zinc Selenium and Vitamin Dmentioning

confidence: 99%

SARS-CoV-2: Nutritional determinants of reducing the risk of infection of the central nervous system

Szponar¹,

Matczuk²

2021

ppn

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Purpose The aim of this study is to assess the nutritional determinants that may contribute to potentially reducing the risk of COVID-19 central nervous system infection or, if infection occurs, to experience it in a mild form. Views In this study, the authors collected data on nutrients that support traditional drug treatment and potentially reduce central nervous system infections, while also indicating the role they play in the central nervous system (CNS). The article points out that long chain polyunsaturated fatty acids polyunsaturated fatty acids, probiotics and prebiotics, as well as vitamin D selenium and zinc play a role in supporting immune function and reducing the risk of CNS infections. It should be noted that, due to the novel nature of the SARS-CoV-2 virus, limited number of studies evaluating the potential impact of dietary components on COVID-19 risk reduction or their adjunctive effect on treatment are available. Therefore, further clinical studies are needed to confirm these results. Conclusions The dietary habits and nutrients described in the article support medical care, including vaccination and other therapies. They are likely to reduce the risk of CNS SARS-CoV-2 infection. The functioning of the physiological gut-brain axis supported by probiotics, polyphenols, certain minerals such as zinc, selenium and vitamin D consumed with the diet, can probably reduce the cost of COVID-19 treatment on the CNS. Also, nutrients other than those mentioned in the article, including vitamins A, E, B 1 , B 6 , B 12 and iron, could potentially reduce the cost of the treatment of this disease.

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Section: Zinc Selenium and Vitamin Dmentioning

confidence: 99%

SARS-CoV-2: Nutritional determinants of reducing the risk of infection of the central nervous system

Szponar¹,

Matczuk²

2021

ppn

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“…In 1934 and 1961 it was shown that this element is also necessary for the proper development of animals and humans [ 5 ]. Zinc is involved in the action of over 300 enzymes that catalyze hydrolysis reactions or the transport of functional groups [ 6 , 7 ]. The daily requirement for zinc, depending on age, ranges from 2 mg for infants to 11–13 mg for adults, including pregnant and breastfeeding women [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

“…Of course, it should be remembered that an excess of zinc and other microelements may be harmful, according to the Paracelsus principle—everything is a poison and nothing is a poison, it is the dose that makes the poison. For example, employees working in zinc smelters are exposed to excessive doses of zinc, where they suffer from an occupational disease called foundry fever [ 6 , 11 , 12 ]. Based on these few examples, it can be seen that controlling the level of zinc as well as a whole range of macro- and microelements is necessary for the proper functioning of living organisms.…”

Section: Introductionmentioning

confidence: 99%

Fluorescent Sensor Based on 1H-Pyrazolo[3,4-b]quinoline Derivative for Detecting Zn2+ Cations

Kolbus,

Uchacz,

Danel

et al. 2024

Molecules

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The photophysical and sensory properties of the donor–acceptor pyrazoloquinoline derivative (PQPc) were investigated using absorption, steady-state, and time-resolved fluorescence measurements. The compound synthesized from commercial, readily available substrates exhibited absorptions in the UV–Vis range, with a maximum of the longwave band around 390 nm. The maximum fluorescence was around 460–480 nm, depending on the solvent. The quantum yield was between 12.87% (for n-hexane) and 0.75% (for acetonitrile) and decreased with increasing solvent polarity. The PET mechanism was implicated as the cause of fluorescence quenching. Divalent ions such as Zn2+, Pb2+, Cd2+, Ca2+, Mg2+, Co2+, Ni2+, and Cu2+ were introduced to study the fluorescent response of PQPc. A 13-times increase in fluorescence quantum yield was observed after the addition of Zn2+ ions. Detailed research was carried out for the PQPc-Zn2+ system in order to check the possibility of analytical applications of PQPc as a fluorescent sensor. A detection limit of Zn2+ was set at the value level 1.93 × 10−7 M. PQPc-Zn2+ complexes had a stoichiometry of 1:1 with a binding constant of 859 M−1. Biological studies showed that the sensor was localized in cells near the membrane and cytoplasm and may be used to detect zinc ions in eukaryotic cells.

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“…ZnT proteins reduce the concentration of zinc in the cytoplasm, either transporting zinc outside the cell or moving it to extracellular fluids, while ZIP proteins have the opposite effect—they allow the influx of zinc from the vessels into the cell. Zinc may be transported from the intestinal lumen into the enterocytes via a non-specific divalent metal transporter (DMT1) [ 7 , 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

The Role of Zinc in Bone Tissue Health and Regeneration—a Review

Molenda

Kolmas

2023

Biol Trace Elem Res

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Zinc is a micronutrient of key importance for human health. An increasing number of studies indicate that zinc plays a significant role in bone tissue’s normal development and maintaining homeostasis. Zinc is not only a component of bone tissue but is also involved in the synthesis of the collagen matrix, mineralization, and bone turnover. It has been demonstrated that zinc can stimulate runt-related transcription factor 2 (Runx2) and promote the differentiation of osteoblasts. On the other hand, zinc has been found to inhibit osteoclast-like cell formation and to decrease bone resorption by stimulating osteoclasts’ apoptosis. Moreover, zinc regulates the RANKL/RANK/OPG pathway, thereby facilitating bone remodeling. To date, not all mechanisms of Zn activity on bone tissue are well understood and documented. The review aimed to present the current state of research on the role of zinc in bone tissue, its beneficial properties, and its effects on bone regeneration. Since calcium phosphates as bone substitute materials are increasingly enriched in zinc ions, the paper included an overview of research on the potential role of such materials in bone filling and regeneration.

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Importance of zinc for the human body in the aspect of zinc supplementation

Cited by 8 publications

References 40 publications

SARS-CoV-2: Nutritional determinants of reducing the risk of infection of the central nervous system

SARS-CoV-2: Nutritional determinants of reducing the risk of infection of the central nervous system

Fluorescent Sensor Based on 1H-Pyrazolo[3,4-b]quinoline Derivative for Detecting Zn2+ Cations

The Role of Zinc in Bone Tissue Health and Regeneration—a Review

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