Important Developments in Romanian Propolis Research

Mărghitaș, Liviu Al.; Dezmirean, Daniel Severus; Bobiş, Otilia

doi:10.1155/2013/159392

Cited by 37 publications

(35 citation statements)

References 55 publications

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“…Los fenoles y flavonoides del propóleos son los mayores responsables de su actividad biológica (43) . Los resultados del contenido de fenoles y de flavonoides totales de EH-M1, EH-M2 y EH-M4 (Tabla 2b) fueron acordes con los reportados por otros autores (17)(44) (45) .…”

Section: Discussionunclassified

Avances en el desarrollo de un biofungicida: Caracterización físico-química y actividad antifúngica de propóleos

et al. 2019

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El propóleos constituye, gracias a sus propiedades antimicrobianas, una alternativa para el control de fitopatógenos. En este trabajo se realizó, mediante técnicas convencionales, la caracterización sensorial y físico-química de cuatro muestras de propóleos provenientes de diferentes regiones de Argentina y de sus respectivos extractos hidroalcohólicos. Asimismo, se evaluó in vitro la actividad antifúngica de los extractos sobre el hongo Penicillium sp. causante de la «mufa del ajo» (Allium sativum). Los propóleos en bruto presentaron aroma resinoso, coloración marrón con diferentes tintes y aspecto de trozos irregulares. El análisis de las muestras evidenció diferencias significativas en los parámetros ceras (9,43-31,16 %), pérdidas por calentamiento (1,04-1,46 %), cenizas (0,98-7,18 %) y temperatura media de fusión (63,16-67,5 °C). En los extractos hidroalcohólicos de propóleos también se detectaron diferencias estadísticas en el extracto seco (5,50-9,30 %), contenido de fenoles (23,44-53,91 mg eq gálico/g propóleos), flavonoides totales (11,23-15,88 mg eq quercetina/g propóleos) e índice de oxidación (2,25-4,33 segundos). Todos los tratamientos a base de extractos de propóleos tuvieron un efecto inhibidor superior al 99 % sobre el desarrollo de unidades formadoras de colonias fúngicas. Los resultados permiten concluir que, si bien los propóleos y extractos analizados en este trabajo presentaron diferentes características, coincidieron en la excelente actividad antifúngica sobre Penicillium sp. Esto demuestra la potencialidad de los propóleos para el desarrollo de un biofungicida de uso agrícola.

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Section: Discussionunclassified

Avances en el desarrollo de un biofungicida: Caracterización físico-química y actividad antifúngica de propóleos

et al. 2019

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“…It seems that naturally bioactive compounds may have a cooperative action with different types of chemotherapeutics. Particularly, Romanian propolis possessed high amounts of biologically active compounds such as phenolic acids, flavonoids (flavonols, flavanones, flavanols), aminoacids and minerals [12,13]. So, the composition of propolis varies according to the species of bee, geographic origin, month of collection, as well as to the solvent used in extraction process -higher content of active substances was obtained when ethanol was used [14].…”

mentioning

confidence: 99%

Novel Formulation Based on Chitosan-Arabic Gum Nanoparticles Entrapping Propolis Extract Production, physico-chemical and structural characterization

Cavalu¹,

Bisboaca²,

Mates³

et al. 2019

Rev. Chim.

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The aim of our study was to prepare and characterize chitosan-based nanoparticles encapsulating propolis extract by ionotropic gelation and glutaraldehyde cross-linking technique. Both spectroscopic (UV-Vis, FTIR) and microscopic techniques (AFM) were applied for structural characterization of nanoparticles, along with entrapment and release study of propolis extract. The physico-chemical properties and morphological features of the obtained nanoparticles demonstrated a good correlation between all the investigated methods. Moreover, the bioactive compounds were stable upon the encapsulation procedure. Propolis release from the polymeric matrix was monitored in both simulated gastric acid and simulated intestinal fluids, concluding that our proposed formulation is suitable for controlled release. These results may provide a novel design, with improved bioavailability, stability and nutritional value of propolis bioactive compounds during processing and storage, with possible applications in food and nutraceutical industries.

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“…In general, it is thought that the appearance of the absorption band at 270-330 nm is attributable to flavonoids and phenols (Mărghitaş et al, 2013) while the absorption band at 230 nm is characteristic for flavone/flavonol by-products (Yang, t al., 2013). Also, it is reported that band with λ max 290 nm, is believed to arise from Hispertin (Makawi et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

“…Also, it is reported that band with λ max 290 nm, is believed to arise from Hispertin (Makawi et al, 2009). Variation in intensity and shift in the absorption band might be attributed to the different antioxidant ratios in flavonoids and phenols (Mărghitaş et al, 2013). A high correlation was found between the UV-Vis spectra of samples and total phenolic compounds that were determined by the Folin-Ciocalteu method (Hamieda et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

Biophysical Studies of Some Bee Products as Radioprotectors

Hamieda

Hassan

Abdou

et al. 2018

Preprint

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The study had been planned to evaluate some antioxidant ingredients in honey and propolis. Also, a study on ionizing gamma irradiated rats was done to assess these antioxidants as radioprotectors. Bioactive ingredients, such as phenols, flavonoids and trace elements, were explored using FTIR, UV-Vis and AAS spectroscopic techniques. Animals were exposed to fractionated gamma radiation doses. Honey, propolis and their combination were administrated before and during the irradiation period. Serum levels of total protein, albumin and uric acid were estimated. Also, the osmotic fragility of Red Blood Corpuscles (RBCs) membranes and a microscopic examination of blood films were investigated. The analysis demonstrated that the level of phenolic, flavonoid and trace elements are higher in propolis than honey. The levels of total protein and albumin decreased post irradiation while the level of uric acid increased. Likewise, osmotic fragility of RBCs membranes was increased with a sticking forming RBCs aggregation. It had been found that administration of the natural antioxidants induced amelioration in most of the studied parameters. It can be concluded that natural antioxidants produced a modulation against oxidative stress induced by ionizing radiation.Summary StatementAssessment of some antioxidant ingredients in honey and propolis. Also, a study on ionizing gamma irradiated rats was done to assess these antioxidants as radioprotectors.

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Important Developments in Romanian Propolis Research

Cited by 37 publications

References 55 publications

Avances en el desarrollo de un biofungicida: Caracterización físico-química y actividad antifúngica de propóleos

Avances en el desarrollo de un biofungicida: Caracterización físico-química y actividad antifúngica de propóleos

Novel Formulation Based on Chitosan-Arabic Gum Nanoparticles Entrapping Propolis Extract Production, physico-chemical and structural characterization

Biophysical Studies of Some Bee Products as Radioprotectors

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