Impracticalities of thiopurine‐S‐methyltransferase determination in daily inflammatory bowel disease practice: authors' reply

Winter, J.; Mills, Peter R.

doi:10.1111/j.1365-2036.2006.02848.x

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2007

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“…(2006) findings (17), Winter et al. (2006) (18) postulated that uptake of TPMT testing by UK gastroenterologists would be higher. In fact, our findings show that 60% of our sample of gastroenterologists in England tested TPMT enzyme‐levels prior to prescribing AZA.…”

Section: Discussionmentioning

confidence: 99%

Current use of pharmacogenetic testing: a national survey of thiopurine methyltransferase testing prior to azathioprine prescription

et al. 2007

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Two-thirds of the consultants surveyed in England are using TPMT enzyme-level testing, prior to AZA treatment. Uptake differs between specialities. High uptake of TPMT enzyme-level testing by dermatologists, compared with gastroenterologists and rheumatologists, may reflect national guidelines advocating its use prior to AZA. Uptake of enzyme-level testing may alter in other specialties as other guidelines are developed.

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Section: Discussionmentioning

confidence: 99%