IMPROVE lifestyle in polycystic ovary syndrome: a systematic strategy

Pup, Lino Del; Cagnacci, Angelo

doi:10.1080/09513590.2021.1871892

Cited by 6 publications

(4 citation statements)

References 26 publications

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“…There are already specific protocols designed to increase dietary adherence, such as the I.M.P.R.O.V.E. strategic, systematic approach, which has been proposed to improve adherence to advised lifestyle for PCOS patients 61 , and applying such protocols to patients who have been screened at the initiation of the treatment to be more likely less adherent to dietary recommendations would likely increase treatment success and thus would certainly be far more cost-effective than the cost of unsuccessful assisted reproduction interventions. Besides identifying the role of dietary adherence specifically mediating the effect of cyclothymic and irritable temperaments on infertility treatment success, our study also sheds light on the need for identifying how psychological factors can be used to screen for behavioral factors mediating their effect in impacting the success of interventions.…”

Section: The Role Of Affective Temperaments In the Success Of Fertili...mentioning

confidence: 99%

Adherence to dietary recommendations mediates the effect of affective temperaments on infertility treatment outcomes

Szabo,

Szigeti F.,

Sipos

et al. 2024

Sci Rep

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Affective temperaments have been shown to robustly affect infertility treatment success. However, identification of possible mediating factors through which they exert their influence is still lacking. A growing number of results suggest that adherence to recommended treatments may be such a mediator, on the one hand, because affective temperaments are known to influence adherence and, on the other hand, because non-adherence negatively influences the treatment outcome. Recommended treatment of infertility involves, beyond medications, dietary and lifestyle changes. The aim of this retrospective cohort study was to evaluate whether adherence to physician-prescribed diet and physical activity recommendations mediates the effect of affective temperaments on infertility treatment outcomes. Among 308 women who underwent infertility treatment in an Assisted Reproduction Center, affective temperaments, adherence to diet, adherence to physical exercise, and infertility treatment success (clinical pregnancy) were assessed besides detailed medical history and demographic parameters. Associations between affective temperaments, adherence to diet and recommended physical activity, and assisted reproduction outcomes were analyzed using generalized linear models and causal mediation analysis. Adherence to physical activity didn’t have an effect, but diet adherence increased the odds of infertility treatment success by 130% suggesting its role as a potential mediator. Based on causal mediation analysis, higher depressive and anxious temperament scores were directly associated with 63% and 45% lower odds of achieving clinical pregnancy, respectively, with effects not mediated by diet adherence. Higher irritable temperament scores indirectly decreased the odds of achieving clinical pregnancy by 14%, mediated by diet adherence; while higher cyclothymic temperament scores decreased the odds of achieving clinical pregnancy both directly by 51% and indirectly, mediated by diet adherence by 11%. Our results suggest that diet adherence mediates the mechanism by which irritable and cyclothymic affective temperaments influence IVF treatment success. Since adherence is a modifiable risk factor of infertility treatment success, screening for affective temperaments may help to identify potentially high-risk non-adherent patient groups and offer patient-tailored treatment, which may help increase the chances of a successful pregnancy and live birth in women undergoing IVF treatment.

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Section: The Role Of Affective Temperaments In the Success Of Fertili...mentioning

confidence: 99%

Adherence to dietary recommendations mediates the effect of affective temperaments on infertility treatment outcomes

Szabo,

Szigeti F.,

Sipos

et al. 2024

Sci Rep

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“…Lifestyle change is the first line of treatment for the management of women with PCOS but is not an alternative to its pharmacological treatment [ 7 ]. Regular physical activity, maintaining appropriate body weight, following healthy dietary patterns and avoiding tobacco use is vital in prevention and treatment of metabolic disorders, and is included in clinical guidelines for various conditions.…”

Section: Lifestyle Changesmentioning

confidence: 99%

“…The four main causes of the physiological basis of PCOS include: disorders of gonadotropin hormonal synthesis; the appearance of insulin resistance; the influence of the present excessive body fat; and finally, the metabolic pathways involved in PCOS (the secretion and activity of insulin, encoding for steroidogenesis, and other metabolic and hormonal pathways) ( Figure 1 ) [ 7 ]. …”

Section: Introductionmentioning

confidence: 99%

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Nutrition Strategy and Life Style in Polycystic Ovary Syndrome—Narrative Review

et al. 2021

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Here we present an extensive narrative review of the broadly understood modifications to the lifestyles of women with polycystic ovary syndrome (PCOS). The PubMed database was analyzed, combining PCOS entries with causes, diseases, diet supplementation, lifestyle, physical activity, and use of herbs. The metabolic pathways leading to disturbances in lipid, carbohydrate, and hormonal metabolism in targeted patients are described. The article refers to sleep disorders, changes in mental health parameters, and causes of oxidative stress and inflammation. These conditions consistently lead to the occurrence of severe diseases in patients suffering from diabetes, the fatty degeneration of internal organs, infertility, atherosclerosis, cardiovascular diseases, dysbiosis, and cancer. The modification of lifestyles, diet patterns and proper selection of nutrients, pharmacological and natural supplementation in the form of herbs, and physical activity have been proposed. The progress and consequences of PCOS are largely modifiable and depend on the patient’s approach, although we have to take into account also the genetic determinants.

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Importance of Nutrition & Diet in PCOS

Tandon

2024

A Guide to Hormonal Dermatology

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IMPROVE lifestyle in polycystic ovary syndrome: a systematic strategy

Cited by 6 publications

References 26 publications

Adherence to dietary recommendations mediates the effect of affective temperaments on infertility treatment outcomes

Adherence to dietary recommendations mediates the effect of affective temperaments on infertility treatment outcomes

Nutrition Strategy and Life Style in Polycystic Ovary Syndrome—Narrative Review

Importance of Nutrition & Diet in PCOS

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