Through the combustion experiments on the cables and servers in a data room, the combustion characteristic parameters of the materials were obtained, and the materials were analyzed and evaluated from the aspects of heat release rate, gas concentration, flue gas temperature, and so on. The results show that network cable and electric cable can be ignited during the cable combustion test. In the overall fire combustion experiment of single server and the server group with three cabinets, the fire process is divided into three stages: initial growth stage, stable combustion stage, and combustion attenuation stage. The heat release rate, flue gas temperature, and CO2 concentration of the overall experiment have three peaks, respectively, 58, 98, and 134 kW; 100°C, 152°C, and 232°C; 1314, 2514, and 2988 ppm. The research results can provide some reference for design of fire protection system in data rooms.