Improved determination of sulpiride in plasma by ion-pair liquid chromatography with fluorescence detection

Nicolas, Patrick; Fauvelle, F.; Ennachachibi, A.; Merdjan, Henri; Petitjean, Olivier

doi:10.1016/s0378-4347(00)83605-1

Cited by 34 publications

(26 citation statements)

References 10 publications

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“…The sensitivity of sulpiride was approximately 10 times higher than those of the HPLC methods [6][7][8][9][10] and was comparable to that reported by Tokunaga et al 11 Also, they use a smaller sample volume, which provided an advantage as compared with the previous method 11 that required 1 ml of plasma for drug analysis.…”

Section: Calibration Curvessupporting

confidence: 64%

Direct Determination of Benzamides in Serum by Column-Switching High-Performance Liquid Chromatography

et al. 2003

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Section: Calibration Curvessupporting

confidence: 64%

Direct Determination of Benzamides in Serum by Column-Switching High-Performance Liquid Chromatography

et al. 2003

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“…The intra-and inter-assay coefficients of variation were 4% and 6% respectively. Serum sulpiride levels were measured by E. R. Squibb and Sons Ltd using the method of Nicolas et al (1986).…”

Section: Methodsmentioning

confidence: 99%

(+)‐sulpiride antagonises the renal effects of gamma‐L‐glutamyl‐L‐dopa in man.

MacDonald

Jeffrey

Freestone

et al. 1988

Brit J Clinical Pharma

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The Royal Infirmary, Edinburgh EH3 9YW 1 y-L-glutamyl-L-dopa (gludopa) was given by intravenous infusion to six healthy saltreplete men on two occasions, with and without pretreatment with (+)-sulpiride. 2 Gludopa increased sodium excretion, glomerular filtration rate and effective renal plasma flow whilst decreasing plasma renin activity. 3 (+)-sulpiride had no significant effect on baseline natriuresis, renal haemodynamics or plasma renin activity, but significantly attenuated the rise in sodium excretion, glomerular filtration rate and effective renal plasma flow produced by gludopa. 4 (+)-sulpiride abolished the acute fall in plasma renin activity seen with gludopa. 5 (+)-sulpiride raised serum prolactin concentration but did not affect the rise in urine dopamine excretion rate caused by gludopa. 6 Gludopa exerts its renal effects by stimulating specific dopamine receptors which are principally of the DA1 subtype.

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“…A reversed phase ion-pair HPLC method developed by Nicolas et al (1986) was used with minor modifications. A liquid chromatograph (Hitachi 655A-11, Japan) equipped with a fluorescence detector (Jasco 820-FP, Japan) was used.…”

Section: Hplc Conditions For Sulpiride Determinationmentioning

confidence: 99%

Improving the Oral Bioavailability of Sulpiride by Sodium Oleate in Rabbits

Naasani

Kohri

Iseki

et al. 1995

Journal of Pharmacy and Pharmacology

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To improve the limited oral bioavailability of sulpiride, a dosage form containing sodium oleate as an absorption enhancer was developed and evaluated using gastric-emptying-controlled rabbits in a cross-over manner. In addition to the known properties of sodium oleate with respect to modifying the permeability of biomembranes, it was found to be capable of improving the physicochemical properties of sulpiride toward a higher lipophilicity (by ion-pair association) and a higher solubility (by micellar solubilization). Nonetheless, the incorporation of sodium oleate with sulpiride as a mixture filled in hard gelatin capsules failed to increase intestinal absorption, whereas the use of enteric capsules, instead of the hard gelatin capsules resulted in a significant increase (P < 0.05) in the oral bioavailability.

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Improved determination of sulpiride in plasma by ion-pair liquid chromatography with fluorescence detection

Cited by 34 publications

References 10 publications

Direct Determination of Benzamides in Serum by Column-Switching High-Performance Liquid Chromatography

Direct Determination of Benzamides in Serum by Column-Switching High-Performance Liquid Chromatography

(+)‐sulpiride antagonises the renal effects of gamma‐L‐glutamyl‐L‐dopa in man.

Improving the Oral Bioavailability of Sulpiride by Sodium Oleate in Rabbits

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