“…The main reasons for the compromise in reproducibility and accuracy, aside from geometric assumptions, lie with the inadequate discrimination of the endocardial border. CE provides better endocardial border delineation than nonenhanced echocardiography (2,15,25,26). CE has been demonstrated to significantly improve agreement in the measurements of LV volumes and LVEF using current reference standards, including cineventriculography, radionuclide ventriculography, electron beam computed tomography and MRI (1,(27)(28)(29)(30).…”