Improved enzymatic assay for hydrogen peroxide and glucose by exploiting the enzyme-mimicking properties of BSA-coated platinum nanoparticles

He, Shao‐Bin; Chen, Rui-Ting; Wu, Yanyu; Wu, Gang-Wei; Peng, Hua-Ping; Liu, Ailin; Deng, Hao‐Hua; Xia, Xing‐Hua; Chen, Wei

doi:10.1007/s00604-019-3939-y

Cited by 31 publications

(15 citation statements)

References 35 publications

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“…70 Different types of MSNPs such as MCM-41, MCM-48, MCM-50, SBA-3, SBA-11, SBA-12, SBA-15, SBA-16, FSM-16, TUD-1, HMM-33, and COK-12 with various shapes and sizes and the established synthesis methods are now available (Figure 5). 92 The multifunctional MSNPs have been widely used for the controlled delivery of various therapeutic agents as well as biomolecules such as optical probes, enzymes, proteins, antibodies, and nucleic acids. 93,94 The smart MSNPs have recently been developed and used for the localized and stimuliresponsive delivery of cargos.…”

Section: Classification Of Npsmentioning

confidence: 99%

Recent Advances in Nanomaterials Development for Nanomedicine and Cancer

Kajani

Javanmard

Asadnia

et al. 2021

ACS Appl. Bio Mater.

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Cancer is considered one of the leading causes of death, with a growing number of cases worldwide. However, the early diagnosis and efficient therapy of cancer have remained a critical challenge. The emergence of nanomedicine has opened up a promising window to address the drawbacks of cancer detection and treatment. A wide range of engineered nanomaterials and nanoplatforms with different shapes, sizes, and composition has been developed for various biomedical applications. Nanomaterials have been increasingly used in various applications in bioimaging, diagnosis, and therapy of cancers. Recently, numerous multifunctional and smart nanoparticles with the ability of simultaneous diagnosis and targeted cancer therapy have been reported. The multidisciplinary attempts led to the development of several exciting clinically approved nanotherapeutics. The nanobased materials and devices have also been used extensively to develop point-of-care and highly sensitive methods of cancer detection. In this review article, the most significant achievements and latest advances in the nanomaterials development for cancer nanomedicine are critically discussed. In addition, the future perspectives of this field are evaluated.

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Section: Classification Of Npsmentioning

confidence: 99%

Recent Advances in Nanomaterials Development for Nanomedicine and Cancer

Kajani

Javanmard

Asadnia

et al. 2021

ACS Appl. Bio Mater.

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“…Since then, the number of such materials has been growing constantly. These include different material types, such as Nafion-cytochrome c [ 85 ], supramolecular complexes of hydrogel [ 86 ], nanocomplexes of lanthanides [ 87 , 88 , 89 , 90 , 91 , 92 ], Co 3 O 4 @CeO 2 hybrid microspheres [ 93 ], transition metal oxides and their composites [ 71 , 94 , 95 , 96 , 97 , 98 , 99 ], as well as noble metals: Au [ 100 ], Fe/Au [ 101 ], Au/Pt [ 102 ], Pt [ 103 , 104 ], Ru [ 105 ], Pt/Ru [ 60 ], Pd, Pd@Pt [ 106 ], Pd/Pt [ 107 ], Pd@γ-Fe 2 O 3 [ 108 ], etc. In the last decade, special interest in bionanotechnology has focused on the use of NZs based on carbon materials such as fullerenes [ 109 ], Prussian blue [ 110 ], TiO 2 [ 111 ] or Fe 2 O 3 /Pt-modified [ 112 ] multi-walled carbon nanotubes, hemin-graphene hybrid nanosheets [ 113 ], Pt/Ru/3D graphene foam [ 114 ], graphene oxide [ 115 ], Au/Pt/Au-graphene oxide nanosheets [ 116 ], Pd-magnetic graphene nanosheets [ 117 ], hemin-graphene-Au hybrid [ 118 ], IrO 2 [ 119 ], Cu-Ag [ 120 ] or Fe 2 O 3 -modified graphene oxide [ 121 ] ( Figure 4 ), Co-modified magnetic carbon [ 122 ], Co 3 O 4 graphene composite [ ...…”

Section: Nanozymes As Peroxidase Mimeticsmentioning

confidence: 99%

Synthesis, Catalytic Properties and Application in Biosensorics of Nanozymes and Electronanocatalysts: A Review

Stasyuk

Smutok

Demkiv

et al. 2020

Sensors

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The current review is devoted to nanozymes, i.e., nanostructured artificial enzymes which mimic the catalytic properties of natural enzymes. Use of the term “nanozyme” in the literature as indicating an enzyme is not always justified. For example, it is used inappropriately for nanomaterials bound with electrodes that possess catalytic activity only when applying an electric potential. If the enzyme-like activity of such a material is not proven in solution (without applying the potential), such a catalyst should be named an “electronanocatalyst”, not a nanozyme. This paper presents a review of the classification of the nanozymes, their advantages vs. natural enzymes, and potential practical applications. Special attention is paid to nanozyme synthesis methods (hydrothermal and solvothermal, chemical reduction, sol-gel method, co-precipitation, polymerization/polycondensation, electrochemical deposition). The catalytic performance of nanozymes is characterized, a critical point of view on catalytic parameters of nanozymes described in scientific papers is presented and typical mistakes are analyzed. The central part of the review relates to characterization of nanozymes which mimic natural enzymes with analytical importance (“nanoperoxidase”, “nanooxidases”, “nanolaccase”) and their use in the construction of electro-chemical (bio)sensors (“nanosensors”).

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“…Unfortunately, most of the reported nanozymes have multi-enzyme properties . Thus, when designing nanozymes to enhance their target mimetic enzyme activity, it is often the case that non-target mimetic enzyme activity is increased simultaneously. , This is undesirable when accurate evaluation is required for real functions, which limits their promising applications. Hence, designing high-performance, specific oxidase nanozymes with no peroxidase-like activity is of great significance.…”

Section: Introductionmentioning

confidence: 99%

Rational Design of N-Doped Carbon Nanocage-Equipped Co-N_x Active Sites for Oxidase Mimicking and Sensing Applications

Wang

et al. 2021

ACS Sustainable Chem. Eng.

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Rational design of high-performance nanozyme is of great significance for sensing applications. Here, N-doped carbon nanocages containing Co-N x active sites (CoN x -NC) were fabricated by simple acid etching of Co@NC, which is the product of Co–Co Prussian blue analogues carbonized in an N2 atmosphere. Both optimized Co@NC-650 and CoN x -NC-650 exhibit catalase- and oxidase-like properties. They rapidly decompose H2O2 into O2 and oxidize colorless 3,3′,5,5′-tetramethylbenzidine (TMB) into a blue product. This enables them with no peroxidase-like activity. The oxidase-like activity of CoN x -NC-650 is 3.9 times that of unetched Co@NC-650. The acid treatment dissolves Co nanoparticles generated during carbonization, forming extra mesoporous structures and increasing the exposure of more Co-N x active species. The Michaelis–Menten constant for CoN x -NC-650 with a TMB substrate is 0.186 mM, which is 3.2 times lower than that of oxidase-mimicking CeO2 nanoparticles, suggesting a higher affinity to TMB. Given its excellent oxidase-like activity, the CoN x -NC-650 was used to sensitively and selectively determine acetylcholinesterase (AChE) activity based on thiocholine inhibition of the TMB color reaction. Thiocholine is produced via hydrolysis of acetylthiocholine catalyzed by AChE. The colorimetric biosensor has a linear response to AChE over 0.6–800 mU L–1 concentration range and a detection limit (3σ) of 0.2 mU L–1. The assay was successfully applied to determine AChE activity in biological samples.

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Improved enzymatic assay for hydrogen peroxide and glucose by exploiting the enzyme-mimicking properties of BSA-coated platinum nanoparticles

Cited by 31 publications

References 35 publications

Recent Advances in Nanomaterials Development for Nanomedicine and Cancer

Recent Advances in Nanomaterials Development for Nanomedicine and Cancer

Synthesis, Catalytic Properties and Application in Biosensorics of Nanozymes and Electronanocatalysts: A Review

Rational Design of N-Doped Carbon Nanocage-Equipped Co-N_x Active Sites for Oxidase Mimicking and Sensing Applications

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Improved enzymatic assay for hydrogen peroxide and glucose by exploiting the enzyme-mimicking properties of BSA-coated platinum nanoparticles

Cited by 31 publications

References 35 publications

Recent Advances in Nanomaterials Development for Nanomedicine and Cancer

Recent Advances in Nanomaterials Development for Nanomedicine and Cancer

Synthesis, Catalytic Properties and Application in Biosensorics of Nanozymes and Electronanocatalysts: A Review

Rational Design of N-Doped Carbon Nanocage-Equipped Co-Nx Active Sites for Oxidase Mimicking and Sensing Applications

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Rational Design of N-Doped Carbon Nanocage-Equipped Co-N_x Active Sites for Oxidase Mimicking and Sensing Applications