Improved exercise performance and quality of life in patients with symptomatic hypertensive left ventricular hypertrophy by VDD pacing: a double-blind randomized cross-over trial

Kass, David A.; Chen, C.-H.; Talbot, Maurice; Nakayama, M.; Kieval, Robert S.; Lima, João Paulo da Silveira Nogueira

doi:10.1016/s0735-1097(98)82272-9

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“…Preliminary 6-month results suggest that long-term pacing in HH-CO patients increases exercise time and produces sustained symptomatic relief. 27 A catheter can be entrapped in the obliterating apex, causing artifactual pressure differences between the apex and the base. However, we used a straight-tipped catheter with several side holes to minimize the probability of entrapment.…”

Section: Study Limitationsmentioning

confidence: 99%

Mechanism of Acute Mechanical Benefit From VDD Pacing in Hypertrophied Heart

et al. 1998

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Section: Study Limitationsmentioning

confidence: 99%

Mechanism of Acute Mechanical Benefit From VDD Pacing in Hypertrophied Heart

et al. 1998

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Pacemakers and defibrillators for congestive heart failure

2001

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Although medical therapy is the primary therapy for patients with heart failure, the use of pacemakers to improve cardiac hemodynamics is under investigation. Despite promising initial results, controlled studies have not verified the benefit of application of VDD or DDD pacing to a nonselected population of severely symptomatic congestive heart failure (CHF) patients to simply shorten their atrioventricular (AV) delay. There is increasing interest in pacing the left side of the heart or simultaneously pacing the right and left ventricles. Early studies suggest that these techniques may produce favorable hemodynamic effects in patients with CHF. Controlled, randomized studies are now underway. Further, it has been shown that sudden cardiac death accounts for 50% of deaths in patients with CHF. The value of an implantable cardioverter defibrillator (ICD) in secondary prevention of sudden cardiac death is well established. The use of ICD for primary prevention of sudden cardiac death in patients with CHF is being actively evaluated. Several large multicenter trials are underway, some combined with biventricular pacing, and should provide useful data in the coming years.

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Improved exercise performance and quality of life in patients with symptomatic hypertensive left ventricular hypertrophy by VDD pacing: a double-blind randomized cross-over trial

Cited by 2 publications

References 0 publications

Mechanism of Acute Mechanical Benefit From VDD Pacing in Hypertrophied Heart

Mechanism of Acute Mechanical Benefit From VDD Pacing in Hypertrophied Heart

Pacemakers and defibrillators for congestive heart failure

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