Bayesian analysis has become increasingly popular in the social-behavioral sciences. Because hypothesis testing has an important place on the mantel of psychological inquiry, an active area of research has been developing Bayesian analogs for commonly used frequentist tests.However, a major hurdle to this endeavour is computing the necessary ingredients, that is the marginal likelihood, resulting in the use of inflexible analytic solutions or approaches that avoid its computation altogether. In a similar spirit, I extend the spike and slab model, widely considered the gold standard for variable selection, to allow for flexible hypothesis testing. This is accomplished by employing multinoulli indicator variables, as opposed to Bernoulli, which results in a general solution for testing any number of hypotheses that correspond to components of a mixture prior distribution. In a motivating example, I first describe the qualitative relation of the proposed methodology to a popular Bayesian $t$-test, including extensions for one-sided and interval hypothesis tests. With the foundation laid, I proceed to a more complex example wherein themultinoulli spike and slab is used to model a correlation matrix, with the goal of testing joint hypotheses. This example investigated the associations among experimental effects from three cognitive inhibition tasks ($N = 121$), where the theoretical expectation is that they will be positively correlated. To the contrary, the results revealed that the null model of no associations better predicted the observed data than the positive effects model.The important topics of model selection and Bayesian model averaging are also discussed. I end with ideas to further extend the multinoulli spike and slab model. In addition, detailed {\tt R} code is provided that can serve as the building block for developing custom Bayesian models.