2005
DOI: 10.1510/icvts.2005.114470
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Improved outcome after repair of descending and thoracoabdominal aortic aneurysms using modern adjuncts

Abstract: Use of perioperative cerebrospinal fluid drainage, distal aortic perfusion and permissive hypothermia result in a low incidence of spinal cord injury and a low operative mortality.

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Cited by 22 publications
(11 citation statements)
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“…Paraplegia remains the most devastating complication after repair of extensive descending thoracic aneurysms (DTA) and thoracoabdominal aortic aneurysms (TAAA). 1 The maintenance of adequate spinal cord oxygenation is critical to the success of open and endovascular repair of TAAAs to prevent spinal cord ischemia when blood flow to the spinal cord is impaired (e.g., by segmental artery occlusion or aortic cross-clamping). Monitoring of spinal cord function using motor evoked potentials (MEP) or somatosensory evoked potentials (SSEP) is widely accepted in the assessment of intraoperative spinal cord viability during aortic procedures, but it requires significant technical effort and invasiveness.…”
Section: Introductionmentioning
confidence: 99%
“…Paraplegia remains the most devastating complication after repair of extensive descending thoracic aneurysms (DTA) and thoracoabdominal aortic aneurysms (TAAA). 1 The maintenance of adequate spinal cord oxygenation is critical to the success of open and endovascular repair of TAAAs to prevent spinal cord ischemia when blood flow to the spinal cord is impaired (e.g., by segmental artery occlusion or aortic cross-clamping). Monitoring of spinal cord function using motor evoked potentials (MEP) or somatosensory evoked potentials (SSEP) is widely accepted in the assessment of intraoperative spinal cord viability during aortic procedures, but it requires significant technical effort and invasiveness.…”
Section: Introductionmentioning
confidence: 99%
“…In the pioneering experience of Svensson et al [9], operative morbidity and mortality were high. However, operative results have been improving because of innovations such as perioperative cerebrospinal fluid drainage, distal aortic perfusion, reattachment of critical intercostal arteries, permissive hypothermia, and hypothermic circulatory arrest [6,7,10,11]. The in-hospital mortality rate is now 4-10%, and paraplegia or paraparesis occurs in only 2.4-4.5% of patients [6,7,10,11].…”
Section: Discussionmentioning
confidence: 99%
“…At this portion of the TEVAR procedure, the blood pressure is increased, the cardiac output is increased, and (on occasion) the hemoglobin concentration is increased to improve blood oxygen delivery to spinal cord. Typically, the patient is allowed briefly to recover from the antihypertensive treatment modalities, aiming for mean blood pressure in 80s to 90s mmHg to reduce the spinal cord ischemia [33]. Increased blood pressure improves the spinal cord perfusion pressure in the anterior spinal artery across the stent-grafted segment of the aorta that now has lack of perfusion from the intercostal arteries [4,13].…”
Section: Periprocedural Hemodynamic Managementmentioning
confidence: 99%