Improved outcome of percutaneous radiofrequency ablation in renal cell carcinoma: a retrospective study of intraoperative contrast-enhanced ultrasonography in 73 patients

Abstract

Intraoperative CEUS can "real-time" monitor the ablated area during PRFA procedure. This technique can help to achieve a higher success rate compared with conventional ultrasound. No impact of intraoperative CEUS has been found on GFR level.

Contrast enhanced ultrasound of renal masses. A reappraisal of EFSUMB recommendations and possible emerging applications.

“…Moreover CEUS allows a "real-time" monitorization of the ablated area during RFA procedure which may provide a higher success rate than in the case of US monitoring [17]. These results were confirmed by another study where CEUS was superior to clasic US monitoring in achieving the local tumour control (100 % vs.87.5%).…”

Contrast enhanced ultrasound in the evaluation and percutaneous treatment of hepatic and renal tumors

“…The reported sensitivity and specificity of CEUS for the evaluation of residual or recurrent RCC are 82.2-100%, and 96.6-100% [39,40,43,44], respectively, with an accuracy of 90.5-98.1% [39,40,43]. The concordance of CEUS with CECT or CEMRI ranges between 80 and 100% [38][39][40][41][42].…”

“…Conversely, CEUS may be more sensitive in the detection of small ablation-related complications, such as kidney hematoma and perirenal effusion [39,40]. Several studies have assessed the use of CEUS from one day to one week after ablation of RCC, and report a high sensitivity, specificity and accuracy for early detection of residual unablated tumor tissue, comparable to CECT and CEMRI [38][39][40][41][42]. 6.…”

Imaging of renal cell carcinoma

“…A meta-analysis including 11 studies showed promising results for using CEUS to distinguish benign and malignant lesions with a pooled sensitivity of 0.88 (95% CI: 0.85À 0.90), pooled specificity of 0.80 (95% CI: 0.75À0.85), and receiver-operator characteristic area under the curve of 0.922 [10]. Ongoing developments for CEUS or Doppler imaging and comparative studies show promising results [6,[8][9][10][11][12][13]. However, in many countries, including the United States, microbubbles are not approved for use in the abdomen and therefore its use has been very limited.…”