Improved patient‐centered care with effective use of Integra® in dermatologic reconstructive surgery

Abstract

With the use of Integra®, the duration of hospitalization was decreased, patients with multi-morbidities were effectively treated, and functionally- and esthetically-satisfactory outcomes were achieved. On the basis of these observations, we discuss points of handling those patients who require rapid and effective surgery and undergo dermatologic surgery using dermal substitutes.

Tissue and Organ Regeneration in Adults

“…Induced regeneration was embodied in an early FDA-approved collagen-glycosaminoglycan scaffold for dermis regeneration that has spawned clinical treatments, such as treatment of massive burns Heimbach et al 1988;Yeong et al 2012), plastic surgery of the skin (Müller et al 2013;Graham et al 2013), and treatment for chronic skin wounds (Gottlieb and Furman 2002;Yao et al 2013). In this approach the normal wound healing process, which leads to wound contraction and scar formation, is circumvented by use of active collagen scaffolds.…”

Report on immediate irradiation of a rapidly growing sarcoma of the scalp prior to wound closure

“…The combination of the dermal substitute and V.A.C. therapy is essential for a good outcome . In the case presented herein, the graft healed without any complications.…”

“…Integra ® (Ratingen, Germany) is suitable for routine use in patients with distinct underlying conditions who are dependent on safe, rapid, and reliable treatment of deep surgical wounds . An established tool in oncology, adjuvant skin irradiation is a reasonable therapeutic option.…”

“…In 2013, we published a large case series of dermatologic surgery patients to determine the usefulness of a dermal substitute (Integra ® ) for routine use in surgical procedures involving dermatologic tumors . Integra ® is one of several dermal substitutes currently available.…”

Operatives Management und Nachsorge freier Spalthauttransplantate in der okuloplastischen Chirurgie

“…dere Körperregionen vorgeschlagene Einsatz von Integra ® (Wundbehandlungsmaterial mit perforierter Biomatrixschicht, enthält biologisch abbaubares Kollagen und Glykosaminoglykane) [3] zur Verkürzung der Hospitalisationsphase und Vermeidung von sekundärer Morbidität sowie deren Komplikationen, ist in der Lidregion ungeeignet. Aufgrund der i. d. R. im Vergleich zu anderen Regionen kleineren Defektgrößen stellt die Anwendung von Spalthauttransplantaten ein in der Ophthalmochirurgie bewährtes Operationsverfahren dar, falls zu wenig Vollhautmaterial aus dem ipsi-oder kontralateralen Oberlid zur Verfügung steht.…”