“…Although clinical studies of lower limb duplex have used PSV ratios of either~2.0 (refs [16][17][18][19]23),~2.5 (refs 15,20,24,25) or~3.0 (ref. 26) to identify significant (>50% diameter reducing) stenoses, very few ,s,2o,2s.27 have used receiver operator characteristic (ROC) analysis to determine the optimum PSV ratio. Ranke et al, 20 Legemate et al" and Leng et aF8 have all shown a good correlation between PSV ratio and arteriographic diameter reduction up to 75% reduction and concluded by ROC analysis that the optimum PSV ratio cut-off for the prediction of a >50% diameter stenosis was 2.4, 2.5 and 3.0 respectively.…”