Improved Rigidin-Inspired Antiproliferative Agents with Modifications on the 7-Deazahypoxanthine C7/C8 Ring Systems

van der Westhuyzen, Aletta E.; Ashraf, Naghmana; Conradie, Daleen; Loots, Leigh; Kaschula, Catherine H.; Pelly, Stephen C.; Frolova, Liliya V.; Landfair, Taylor; Shuster, Charles B.; Betancourt, Tania; Kornienko, Alexander; van Otterlo, Willem A. L.

doi:10.1021/acs.jmedchem.3c02473

J. Med. Chem.

2024

DOI: 10.1021/acs.jmedchem.3c02473

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Improved Rigidin-Inspired Antiproliferative Agents with Modifications on the 7-Deazahypoxanthine C7/C8 Ring Systems

Aletta E. van der Westhuyzen,

Naghmana Ashraf,

Daleen Conradie

et al.

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Rh(iii)-catalyzed regioselective C–H activation/[3 + 2] cyclization of KHAs with iodonium ylides accessing pyrimido[1,2-a]indole derivatives

Luo,

Qi,

Chen

et al. 2024

Org. Chem. Front.

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Rh(iii)-catalyzed regioselective C–H activation/[3 + 2] cyclization of KHAs with iodonium ylides accessing pyrimido[1,2-a]indole derivatives

Luo,

Qi,

Chen

et al. 2024

Org. Chem. Front.

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show abstract

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Improved Rigidin-Inspired Antiproliferative Agents with Modifications on the 7-Deazahypoxanthine C7/C8 Ring Systems

Cited by 1 publication

References 65 publications

Rh(iii)-catalyzed regioselective C–H activation/[3 + 2] cyclization of KHAs with iodonium ylides accessing pyrimido[1,2-a]indole derivatives

Rh(iii)-catalyzed regioselective C–H activation/[3 + 2] cyclization of KHAs with iodonium ylides accessing pyrimido[1,2-a]indole derivatives

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