Improved Surgical Treatment of Familial Exudative Vitreoretinopathy in Children

Clinical Characteristics and Surgical Management of Familial Exudative Vitreoretinopathy–associated Rhegmatogenous Retinal Detachment

“…[7][8][9] The surgical management of FEVR-associated tractional or exudative retinal detachment is more often discussed in the previous literatures from western countries. 6,10,11 However, in the report from Japan by Ikeda et al, 12 FEVRassociated RRD comprised most of the cases in their series. In the present study, we collected only cases with FEVR-associated RRD to investigate its clinical characteristics and surgical outcomes.…”

“…[7][8][9] Familial exudative vitreoretinopathy-associated retinal detachment includes rhegmatogenous, tractional, and exudative retinal detachment and was used to be thought of as an uncommon mainly tractional origin disorder with a limited surgical successful rate and guarded visual outcome. 5,6,10,11 However, Ikeda et al 12 reported a series of FEVR-associated retinal detachments, which was largely composed of cases of rhegmatogenous origin with vitreous opacity, posterior breaks, giant tear, or proliferative vitreoretinopathy (PVR). Vitrectomy and scleral buckling procedures successfully repaired the retinal detachments in more than 80% of the eyes operated on.…”

Linkage and candidate gene analysis of autosomal‐dominant familial exudative vitreoretinopathy

“…The biochemical basis of ad FEVR is unknown. Although current surgical techniques have improved visual impairments, amblyopia, reproliferation, and vitreous hemorrhage may cause additional problems [18]. As part of our continuing efforts toward cloning the ad FEVR gene, in this report we have carried out linkage analysis using microsatellite markers.…”

Netzhautablösung im Kindesalter

“…Bei Kindern unter 3 Jahren sind die fibrovaskulären Proliferationen besonders reich an vaskulären Bestandteilen, mit zunehmendem Lebensalter nehmen die fibrotischen Anteile zu [56]. Die Ergebnisse der vitreoretinalen Chirurgie bei FEVR sind begrenzt; Amblyopie, Reproliferationen und Glaskörperblutungen limitieren einen langfristigen Visusanstieg [58,59].…”