2023
DOI: 10.1002/pbc.30712
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Improved survival of children and adolescents with classical Hodgkin lymphoma treated on a harmonised protocol in South Africa

Jennifer Geel,
Anel van Zyl,
Jan du Plessis
et al.

Abstract: BackgroundHistoric South African 5‐year overall survival (OS) rates for Hodgkin lymphoma (HL) from 2000 to 2010 were 46% and 84% for human immunodeficiency virus (HIV)‐positive and HIV‐negative children, respectively. We investigated whether a harmonised treatment protocol using risk stratification and response‐adapted therapy could increase the OS of childhood and adolescent HL.MethodsSeventeen units prospectively enrolled patients less than 18 years, newly diagnosed with classical HL onto a risk‐stratified, … Show more

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